Amino acid sequences from a cell cycle control protein from a patient with cancer and a healthy person are aligned. The sequence from the cancer patient indicates one amino acid has changed from phenylalanine (Phe) to leucine (Leu). A mutation in the cancer patient's DNA must have taken place. Identify the result of this DNA change in the mRNA codon that led to this change in the protein sequence. Use the codon table to help you.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Amino acid sequences from a cell cycle control protein from a patient with cancer and a healthy person are aligned. The sequence from the cancer patient indicates one amino acid has changed from phenylalanine (Phe) to leucine (Leu). A mutation in the cancer patient's DNA must have taken place. Identify the result of this DNA change in the mRNA codon that led to this change in the protein sequence. Use the codon table to help you.

 

UUU altered to UUA

CAA altered to UUU

UUU altered to UAU

Amino acid sequences from a cell cycle control protein from a patient with cancer and a healthy person are aligned. The sequence from the cancer patient indicates one amino
acid has changed from phenylalanine (Phe) to leucine (Leu). A mutation in the cancer patient's DNA must have taken place. Identify the result of this DNA change in the MRNA
codon that led to this change in the protein sequence. Use the codon table to help you.
second letter
UUU )
Phe
UCU
UAU
Tyr
UAC
UGU
Cys
C
UUC
UCC
UGC
Ser
UAA stop |UGA stop | A
UAG stop UGG Trp
UUA
UCA
Leu
UUG
UCG
G
CGU
CGC
CUU
CCU
CAU
U
His
CUC
ССС
САС
CUA
Leu
Pro
CGA
Arg
А
ССА
САА
Gln
CA .
CUG
CCG J
CGG
G
AUU
ACU
AAU
AGU 1
fAsn
Lys
Ser
AUC Ile
A
AUA
АСC
ААС
AGC
Thr
AAA 1
AAG JLYS AGG Arg
ACA
AGA
A
AUG Met ACG
G
GUU
GCU
GAU
GGU
Asp
GAC,
GGC
Gly
A
GUC
GCC
Val
GUA
Ala
GCA
GAA
Glu
GGA
GUG
GCG
GAG
GGG
G
first letter
third letter
Transcribed Image Text:Amino acid sequences from a cell cycle control protein from a patient with cancer and a healthy person are aligned. The sequence from the cancer patient indicates one amino acid has changed from phenylalanine (Phe) to leucine (Leu). A mutation in the cancer patient's DNA must have taken place. Identify the result of this DNA change in the MRNA codon that led to this change in the protein sequence. Use the codon table to help you. second letter UUU ) Phe UCU UAU Tyr UAC UGU Cys C UUC UCC UGC Ser UAA stop |UGA stop | A UAG stop UGG Trp UUA UCA Leu UUG UCG G CGU CGC CUU CCU CAU U His CUC ССС САС CUA Leu Pro CGA Arg А ССА САА Gln CA . CUG CCG J CGG G AUU ACU AAU AGU 1 fAsn Lys Ser AUC Ile A AUA АСC ААС AGC Thr AAA 1 AAG JLYS AGG Arg ACA AGA A AUG Met ACG G GUU GCU GAU GGU Asp GAC, GGC Gly A GUC GCC Val GUA Ala GCA GAA Glu GGA GUG GCG GAG GGG G first letter third letter
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