Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 16.1, Problem 1TYK
Which of the following is an epigenetic change that alters gene expression?
- DNA methylation
- chromatin remodeling
- covalent histone modification
- localization of histone variants
- all of the above
Expert Solution & Answer
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Check out a sample textbook solutionStudents have asked these similar questions
Epigenetic phenomena involve
DNA methylation and histone acetylation
genetic mutation
chromosomal rearrangements
gene inversions
Which of the following is true about epigenetic modifications?
-Epigenetic modifications always repress transcription
-Epigenetic modifications are irreversible
-Epigenetic modifications only occur on the tails of histone proteins
-Epigenetic modifications influence the relationship between DNA and
histone proteins
Possible genetic modifications that can cause epigenetic changes in gene expression include:
A- all answers are correct
B- histone acetylation
C- chromatin remodeling
D- histone variant localization 
e- DNA methylation
Chapter 16 Solutions
Principles of Biology
Ch. 16.1 - Which of the following is an epigenetic change...Ch. 16.2 - If you crossed an Igf 2 Igf 2- male mouse to an...Ch. 16.2 - Prob. 1TYKCh. 16.2 - Prob. 2TYKCh. 16.3 - Prob. 1CCCh. 16.3 - Prob. 1TYKCh. 16.3 - Which of the following statements regarding...Ch. 16.4 - Prob. 1TYKCh. 16.4 - Prob. 2TYKCh. 16.5 - Prob. 1BC
Ch. 16.5 - Prob. 1CCCh. 16.5 - Prob. 1TYKCh. 16.5 - Prob. 2TYKCh. 16.6 - Prob. 1CCCh. 16.6 - Prob. 1BCCh. 16.6 - Prob. 1TYKCh. 16.6 - Genes that are linked do not conform to Mendels...Ch. 16 - Which of the following is an example of an...Ch. 16 - In mice, the allele of the Igf2 gene that is...Ch. 16 - Prob. 3TYCh. 16 - The marking process for genomic imprinting...Ch. 16 - According to Mary Lyons hypothesis, the patchwork...Ch. 16 - Prob. 6TYCh. 16 - Prob. 7TYCh. 16 - Prob. 8TYCh. 16 - Prob. 9TYCh. 16 - Prob. 10TYCh. 16 - Prob. 1CCQCh. 16 - Prob. 2CCQCh. 16 - Prob. 3CCQCh. 16 - Prob. 1CBQCh. 16 - Prob. 2CBQ
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- Which of the following is a method through which cells can control their gene expression? Increase a gene's stability using post-translational modifications Epigenetic modifications of the DNA or histones to regulate DNA avilability phosphorylation of thymidines formation of crosslinks between the DNA strands and the histonesarrow_forwardMatch the following changes with the correct responses. (Some answers may be used more than once. Some answers may not be used.) Deacetylation of histones Methylation of cytosines a single nucleotide polymorphism, where adenine may be present instead of cytosine phosphorylation of cytosines is an epigenetic change that is an epigenetic change that [Choose ] is an epigenetic change that results in decreased gene transcription is not an epigenetic change ✓ is an epigenetic change that results in increased gene transcription is an epigenetic change that could either increase or decrease gene transcriptionarrow_forwardThe diagram below shows the structure of DNA from the level of a gene to a condensed mitotic chromosome. At each of the four locations marked, indicate how a gene may be regulated by selecting from the choices given. Some answer choices may fit into more than one position; however, you should use each answer choice only once. Choices given: Alternative splicing within the gene sequence can lead to different forms of mRNA. A promoter region can be blocked by another protein. Histone deacetylation can prevent DNA from unwinding. A regulatory region can be bound and increase transcription rates.arrow_forward
- Which of the following is not a control of gene transcription? The repression of a gene by the binding of a transcription factor to a silencer region Methylation of promotor sequences The stabilization of the initiation complex by transcription factors to allow RNA polymerase to begin replication The conversion of heterochromatin to euchromatin through histone demethylation The binding of an inhibitory protein to the 3' UTRarrow_forwardThe following image shows the 'beads-on-a-string' model of DNA and the effects of histone modification on chromatin structure. What effect does histone acetylation have on Gene 1? Gene 1 De-acetylation Acetylation Ac Ac Gene 1 Ac Ac Ac O Acetylation increases expression of Gene 1 O Acetylation decreases expression of Gene 1 O Acetylation causes a mutation in Gene 1 O There is no way to tell from this figurearrow_forwardEpigenetic changes in chromatin remodelling which selectively PREVENTS transcription Acetylation and phosphorylation of certain histone proteins Methylation Group of answer choices NEITHER 1 NOR 2 2 ONLY 1 AND 2 1 ONLYarrow_forward
- The following is true about epigenetic gene control: O epigenetic changes to the chromatin may result from childhood development epigenetic changes to the chromatin may result from chemicals in the environment O epigenetic changes to the chromatin may result in cancer O An example of a chromatin change is DNA methylation that prevents gene expression from that area of the DNAarrow_forwardYou discover a histone variant that has more positive charge than conventional histone proteins. What effect do you predict this histone variant would have when it is inserted into chromatin? A decrease in the strength of histone-DNA interaction, making chromatin less condensed and increasing gene expression An increase in the strength of histone-DNA interaction, making chromatin less condensed and decreasing gene expression An increase in the strength of histone-DNA interaction, making chromatin more condensed and decreasing gene expression O A decrease in the strength of histone-DNA interaction, making chromatin less condensed and decreasing gene expressionarrow_forwardWhat are the details of the epigenetic processes involved in gene regulation of Histone Modification and DNA methylation? Summarizing these concepts please: All possible enzymes involved ; Reader/writer/eraser designation for the enzyme; Effect on gene expression or consequences; function of the modificationarrow_forward
- Which of the following proteins preserves an epigenetic alteration of DNA? O MYOD O Ey O HAT (histone acetyltransferase) O maintenance methyltransferase de novo methyltransferasearrow_forwardWhich of the following is likely to be transcriptionally expressed? euchromatin and DNA with methyl groups euchromatin DNA with methyl groups DNA with acetylated histones euchromatin and DNA with acetylated histonesarrow_forwardEpigenetic changes in gene regulation are caused by ________. missing nucleotides or chromosomes missing nucleotides or chromosomes mutations of the nucleotide sequence mutations of the nucleotide sequence modifications to histones and the DNA, but not the nucleotide sequence itselfarrow_forward
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