Using figure (a) above as guide, list the five components in the CRISPR-Cas9 bacterial defense system used against bacteriophage infection. In 25 words or less describe the role of each component of the system.(1)(2)(3)(4)(5) a.RecognitionlobeNucleaselobeCas9 ProteinTarget DNAstrand3'5'NontargetDNA strand5'3'CRISPR RNA(crRNA) sequence5'20-nucleotidebase-paired region betweencrRNA and target DNAtracrRNAsequence3'5'3'Photospacer adjacentmotif (PAM)

CRISPR is a acronym for Clustered regularly interspaced short palindromic repeats. It forms a very…

Using figure (a) above as guide, list the five components in the CRISPR-Cas9 bacterial defense system used against bacteriophage infection. In 25 words or less describe the role of each component of the system. (1) (2) (3) (4) (5)

Using figure (a) above as guide, list the five components in the CRISPR-Cas9 bacterial defense system used against bacteriophage infection. In 25 words or less describe the role of each component of the system. (1) (2) (3) (4) (5)

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter30: Protein Synthesis

Section: Chapter Questions

Problem 1P

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Concept explainers

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.

Question

a.
Recognition
lobe
Nuclease
lobe
Cas9 Protein
Target DNA
strand
3'
5'
Nontarget
DNA strand
5'
3'
CRISPR RNA
(crRNA) sequence
5'
20-nucleotide
base-paired region between
crRNA and target DNA
tracrRNA
sequence
3'
5'
3'
Photospacer adjacent
motif (PAM)

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