True or False: In non-disseminated infections, Mycobacterium species are restrained by type-1 responses which increase macrophage phagocytic activity, NK and T cell activation. True or False: The low-affinity Fcε receptor (FcεRII/CD23) on mast cells will bind to IgE in tissues in the absence of antigen.

True or False: In non-disseminated infections, Mycobacterium species are restrained by type-1 responses which increase macrophage phagocytic activity, NK and T cell activation. True or False: The low-affinity Fcε receptor (FcεRII/CD23) on mast cells will bind to IgE in tissues in the absence of antigen.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter17: Genes And The Immune System

Section: Chapter Questions

Problem 31QP

See similar textbooks

Similar questions

Strep throat is commonly caused by group A Streptococcus bacteria. A common symptom of strep throat is the presence of swollen lymph nodes in the neck. This symptom usually peaks about 2–4 days after the onset of the infection, and is due to: Damage to the pharyngeal epithelium by the bacteria Release of bacterial PAMPs leading to inflammatory cytokine production Trapping and activation of antigen-specific lymphocytes in the lymph nodes of the neck Recruitment of neutrophils to the lymph nodes of the neck Recruitment of circulating macrophages to the lymph nodes of the neck
Describe how phagocytes recognize foreign cells. Explain the mechanism phagocytes use to kill engulfed cells. List some ways pathogens avoid the consequences of phagocytosis. Describe the cause, advantages and disadvantages of fever. Define complement and its role in host defense
Innate lymphoid cells reside primarily in tissues such as the lungs, the lining of the gastrointestinal tract, and the skin, because these sites represent the major routes of entry of pathogens into the body. Several different subsets of innate lymphoid cells exist, and each is specialized to respond to a category of pathogen (e.g., viruses, extracellular bacteria, helminthic parasites, etc). a) True b) False
Describe in chronological order the steps involved in the recruitment of neutrophils to infected tissue sites during an innate immune response. Use the following terms in your description: rolling adhesion, tight binding, extravasation, migration, inflammatory mediators, integrins, adhesion molecules, chemokines, selectins, sialyl-Lewisx, and basement membrane proteases.
Both antibodies and particular complement proteins, such as c3b, are capable of aiding phagocytes in attaching to bacteria. What term best describes these? O 1) opsonins O 2) haptens O 3) pyogens O 4) perforins
Complement is an integral part of the innate immune response to bacteria . One of its mechanisms of action is to behave as an anaphylatoxin Describe the anaphylatoxic effects of complement identifying which components are activated.
Which of the following statements regarding phagocyte recognition of pathogens is TRUE? TLRS in the phagocyte cytoplasmic membrane bind surface structures of microbes. O TLRS on the surface of microbes trigger the accumulation of opsonins. O Lectins on the surface of microbes are bound by chemokine receptors. NOD proteins on the surface of microbes are detected by TLRS. Question 3 A person has a disease that has activated the first line of defense. Which of the follca
Name two cytokines that are thought to be involved in the inflammatory response to viruses (cite your source). Describe a component of the innate immune response to viral infection (name it and explain how it works. Be sure you are talking about something that protects you from viruses.)
Opsonization of pathogens by both antibodies and complement proteins (C3b) leads to uptake and destruction of the pathogen by phagocytic cells that express both Fc receptors and complement receptors. Which of the following in the figure below is the most efficient form of dual opsonization of the pathogen by antibody and C3b to maximize phagocytosis?
Draw a figure illustrating the sequence of events in a typical inflammatory response to a bacterial infection caused by injury to the skin (in 3 main stages). Include a note at top of figure: Is this an example of an innate response or adaptive immune response? Include the following structures/cells/chemicals: epidermis, dermis, splinter contaminated with bacteria puncturing skin, macrophages, mast cells, neutrophils, nitric oxide (as blue dots), endothelial cells lining capillary, red blood cells within capillary, histamine (as green dots). Under each stage, describe the events occurring in the 3 main stages: Stage 1: What do mast cells and endothelial cells produce in initial response to injury? What do the chemicals produced by the cells do? Stage 2: What happens to capillaries? What leaks out of capillaries to enter the site of the wound? Stage 3: What do neutrophils and macrophages do? What happens to capillaries at this point?
The effector mechanisms that are recruited to clear an infection depend on the infectious agent. In addition to producing distinct innate responses locally at the site of infection, the different cytokines produced during type I, type 2, or type 3 immune responses also induce distinct adaptive immune responses that are tailored to the eradication of the three different classes of pathogens. One example is the production of different classes of antibodies during type I, type 2, or type 3 responses. Which step during the induction of the adaptive immune response is the key to generating and coordinating the three different immune modules?
Which of the following statements is NOT correct? Group of answer choices -Natural killer cells are cytolytic lymphocytes that mediate ADCC -Neutrophils carry out phagocytosis of C3b-tagged particles -Macrophages carry out phagocytosis of C3b-tagged particles -Mast cells produce granules containing the cytotoxin perforin -B lymphocytes express a receptor for complement proteins