The growth of hybridoma cells, producing a monoclonal antibody, was monitored for 4 and a half days, and the results obtained are listed in the following table: time (days) nº cel/mL x 106 ln nº cel 0 0,45 -0,79851 0,2 0,52 -0,65393 0,5 0,65 -0,43078 1 0,81 -0,21072 1,5 1,22 0,198851 2 1,77 0,57098 2,5 2,13 0,756122 3 3,55 1,266948 3,5 4,02 1,391282 4 3,77 1,327075 4,5 2,2 0,788457 What is the maximum specific rate (µmax) of growth of these cells per day? what is the doubling time of these cells (in days)
The growth of hybridoma cells, producing a monoclonal antibody, was monitored for 4 and a half days, and the results obtained are listed in the following table: time (days) nº cel/mL x 106 ln nº cel 0 0,45 -0,79851 0,2 0,52 -0,65393 0,5 0,65 -0,43078 1 0,81 -0,21072 1,5 1,22 0,198851 2 1,77 0,57098 2,5 2,13 0,756122 3 3,55 1,266948 3,5 4,02 1,391282 4 3,77 1,327075 4,5 2,2 0,788457 What is the maximum specific rate (µmax) of growth of these cells per day? what is the doubling time of these cells (in days)
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 4.5P
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The growth of hybridoma cells, producing a monoclonal antibody, was monitored for 4 and a half days, and the results obtained are listed in the following table:
time (days) |
nº cel/mL x 106 |
ln nº cel |
0 |
0,45 |
-0,79851 |
0,2 |
0,52 |
-0,65393 |
0,5 |
0,65 |
-0,43078 |
1 |
0,81 |
-0,21072 |
1,5 |
1,22 |
0,198851 |
2 |
1,77 |
0,57098 |
2,5 |
2,13 |
0,756122 |
3 |
3,55 |
1,266948 |
3,5 |
4,02 |
1,391282 |
4 |
3,77 |
1,327075 |
4,5 |
2,2 |
0,788457 |
What is the maximum specific rate (µmax) of growth of these cells per day?
what is the doubling time of these cells (in days)?
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