How do ATP levels regulate glycolysis? 00 High levels of ATP enhance glycolysis ATP levels do not affect glycolysis. High levels of ATP inhibit glycolysis.

Human Physiology: From Cells to Systems (MindTap Course List)
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Author:Lauralee Sherwood
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Chapter2: Cell Physiology
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How do ATP levels regulate glycolysis?
000
High levels of ATP enhance glycolysis...
ATP levels do not affect glycolysis.
High levels of ATP inhibit glycolysis.
Transcribed Image Text:How do ATP levels regulate glycolysis? 000 High levels of ATP enhance glycolysis... ATP levels do not affect glycolysis. High levels of ATP inhibit glycolysis.
The graph shows the effect of ATP on the allosteric enzyme phosphofructokinase-1 (PFK-1).
PFK-1 activity (% of Vmax)
100
80
60
40
20
0
Low
[ADP]
[ATP]
High
[ADP]
For a given concentration of fructose 6-phosphate, the PFK-1 activity increases with increasing concentrations of ATP, but there
is a point beyond which increasing the concentration of ATP inhibits the enzyme.
Transcribed Image Text:The graph shows the effect of ATP on the allosteric enzyme phosphofructokinase-1 (PFK-1). PFK-1 activity (% of Vmax) 100 80 60 40 20 0 Low [ADP] [ATP] High [ADP] For a given concentration of fructose 6-phosphate, the PFK-1 activity increases with increasing concentrations of ATP, but there is a point beyond which increasing the concentration of ATP inhibits the enzyme.
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