4. Which step in up/downstream processing consists of purification and buffer exchange?

What is the importance of non-aqueous titrations in pharmaceutical analysis?

Mention the types of volumetric titration and briefly point out their differences.

A 0.300-g feed sample is analyzed for its protein content by the modified Kjeldahl method. If 25.0 mL of 0.100 M HCl is required for titration, what is the percent protein content of the sample?

Suppose that extra volume (more than the actual volume) of 0.2 M NaOH solution was used to reach the end-point in the titration process for the determination of the % purity of aspirin sample (0.5 g). Which of the following is correct? The calculated and the actual percent purity values for the aspirin sample will be the same, since the extra added volume of NaOH solution has no effect on the % purity determination for the aspirin sample. We need to know the actual volume (the real volume that should be used in titration) as well as the used volume of NaOH solution to make a true comparison between the actual and the calculated % purity values for the aspirin sample. The calculated % purity value will be lower than the actual % purity value for the aspirin sample. The calculated % purity value will be higher than the actual % purity value for the aspirin sample.

Definition/explanation of titer in chemistry.

Trial 1 Trial 2 Trial 3 Initial burette reading (mL) 2.29   1.41   1.95   Molarity of NaOH (M) 0.100   0.100   0.100   Volume of vinegar sample (mL) 5.00   5.00   5.00   Final burette reading (mL) 50.37   49.39   49.84 Table 2. Titration data   Trial 1 Trial 2 Trial 3 Initial burette reading (mL) 2.29   1.41   1.95   Molarity of NaOH (M) 0.100   0.100   0.100   Volume of vinegar sample (mL) 5.00   5.00   5.00   Final burette reading (mL) 50.37   49.39   49.84   Expected color at end point       Volume of NaOH used (mL) 48.08   47.98   47.89  Compute for the ff: a.   Average moles of acetic acid (mol)? b.  Average molarity of acetic acid (M)? c.  Average molarity of acetic acid (M)?

Which of the following is a good description of a standard solution as a titrant? a) selectively reactive with the analyte b) only reacts with the matrix c) oxidize when exposed to air d) reacts very slowly but completely

Which of the following steps MUST be done prior to titration of an analyte? I. Prepare a standardized solution II. Wash the burette with a standardized solution III. Fill the burette to the 50-mL mark IV. Prepare a contrast paper to determine burette volume and titration endpoint I, Il and IV only 1, III and IV only II, III and IV only O I, II, and III only

Topic: Standardization of acid and base with back titration Note: Include up to 4 decimal places Kindly explain the process Thank you!