Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Textbook Question
Chapter 13, Problem 20P
A study was performed assessing the association between lifetime analgesic intake and change in estimated glomerular filtration rate (GFR) as measured from two blood samples obtained in 1989 and 2000 among 1645 participants in the Nurses’ Health Study (Curhan, et al. [45]). GFR is a commonly used index of kidney
Provide a 95% CI for the OR computed in Problem 13.19.
13.19 What is the estimated odds ratio for being a case comparing Group D to Group A?
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HB = Hemoglobin
RER = Respiratory exchange
ID
Change in
HB
Obese
RER > 1.1
ratio
No
No
1
-1.4
No
-1.5
No
Yes
No
Yes
3
-2
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4
-2.1
No
-1.9
Yes
Yes
No
-1.6
-1.8
-0.8
6
7
No
Yes
No
Yes
8
9.
-1
No
No
-1.2
No
Yes
10
11
No
No
-0.8
-1.5
12
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13
14
-1.4
-2.6
-1.7
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In 2007, a university study was published investigating the crash risk of alcohol impaired driving.
Data from 2,871 crashes were used to measure the association of a person’s blood alcohol level (BAC) with the risk of being in an accident. The table below shows results from the study.
BAC
0
.01
.03
.05
.07
.09
.11
.13
.15
.17
.19
.21
risk
1
1.03
1.06
1.38
2.09
3.54
6.41
12.6
22.1
39.05
65.32
99.78
a. Find the best fit exponential model for the risk of having an accident based on your BAC.
b. Use your model to predict the relative risk of having an accident for a person with a BAC of 0.08 which is the legal limit in GA.
c. What BAC would make you 50 times more likely to have an accident than someone who has not been drinking?
Chapter 13 Solutions
Fundamentals of Biostatistics
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