Which is the most polar compound in the aldol reaction: the ketone, the aldehyde, or the product? Explain. 8.1. oba H NaOH EtOH, A R R R R = F, H, CH 3, OCH 3 < >
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- (19, 5) Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol or enone below. You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. FOR E/Z stoichiometry one: Consider E/Z stereochemistry of alkenes. Draw the enolate ion in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu.In micxed aldol condensation of acetone with excess benzaldehyde in the presence of NaOH. what is the approximate pkA of acetone 15 20 5 10(19, 5) Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol or enone below. You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. Draw one structure per sketcher.
- Draw the Configuration of the D-Family of Aldoses in a short bond paper (fit in 1 page only) Label properly, thank you!1. what is the Nature of the leaving group (LG)? 2. what is the relative size of activation energy (Ea) for each reaction? 3. what is the Hammond's postulate? 4. what are the Relative thermodynamic stability of the reactive intermediates? 5. what is Influence of the solvent (if given) on the reactions and intermediates?Your aldol condensation procedure calls for refluxing vanillin in acetone and NaOH for an hour. Whatmight happen if you didn’t heat the reaction, or heated it for too short a time? a) A mixture of aldol products and hydroxyketone intermediates would form.b) No reaction would occur, as the heat is needed to deprotonate the acetone.c) The reaction would still be successful.d) No reaction would occur, as the heat is needed to dissolve the NaOH.
- In micxed aldol condensation of acetone with excess benzaldehyde in the presence of NaOH. Draw the acetone's conjugate baseWhich compound forms the higher concentration of hydrate at equilibrium, PhCOCHO or PhCH2CHO? Explain your reasoning.Using the pKa values of the conjugate acids of the leaving groups (the pKa of HBr is -9, and the pKa of H2O is 15.7), explain the difference in reactivity between CH3Br and CH3OH in a nucleophilic substitution reaction.
- what is the expected product a for the following crossed aldol reaction? note formation of the enolate is carried out under irreversible conditions h3c o ch3 lda *not all answer choices included in picExplain the E2 mechanism (bimolecular elimination) of of Elimination ?please explain why this happends, im having trouble in this section. Part A Chymotrypsin, an enzyme that hydrolyzes peptide bonds in proteins, functions in the small intestine at an optimum pH of 7.7 to 8.0. How is the rate of the chymotrypsin-catalyzed reaction affected by each of the following conditions?
