What is the relationship between recombination frequency and a centiMorgan?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter4: Basic Immunology And Immunohematology
Section4.6: Abo Grouping
Problem 6RQ
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What is the relationship between recombination frequency and a
centiMorgan?

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Step 1

Introduction 

One gene/allele can affect the inheritance pattern of other gene present nearby on the same chromosome as Genes can be linked or autonomous/Un-linked. When the genes/alleles segregate during the formation of gametes, those genes are known as autonomous or Unlinked genes while if one gene influence the inheritance pattern of other gene present in a close proximity on the same chromosome then these genes are called as Linked genes and phenomenon is referred as Linkage.

Linkage can be of two types:

  • Coupling: when the linkage occurs either between two dominant alleles or two recessive allele.
  • Repulsion: when the linkage occurs between dominant and recessive alleles.

 

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