What is the most likely diagnosis of this individual's disorder? What mechanisms regulate the production and release of serum T, and TSH? What other conditions can lead to an increase in serum TSH levels?

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter23: Endocrine System Drugs
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can I have help with the following 3 questions??? 

A 10-year-old girl exhibited the following symptoms at her
pediatrician's office: failure to gain height, obvious weight
gain with no change in diet, lethargy, weakness, and some
impairment of school performance. Following thyroid
hormone analysis, the following results were obtained:
decreased thyroxine (T,) level, decreased triiodothyronine
(T3) level, elevated thyrotropin [also referred to as thyroid-
stimulating hormone (TSH)], and a positive thyroid
microsomal antibody titer of 1:3000. On physical
examination, the thyroid gland was observed to be
enlarged.
Questions
What is the most likely diagnosis of this
individual's disorder?
What mechanisms regulate the production and
release of serum T, and TSH?
What other conditions can lead to an increase in
serum TSH levels?
Transcribed Image Text:A 10-year-old girl exhibited the following symptoms at her pediatrician's office: failure to gain height, obvious weight gain with no change in diet, lethargy, weakness, and some impairment of school performance. Following thyroid hormone analysis, the following results were obtained: decreased thyroxine (T,) level, decreased triiodothyronine (T3) level, elevated thyrotropin [also referred to as thyroid- stimulating hormone (TSH)], and a positive thyroid microsomal antibody titer of 1:3000. On physical examination, the thyroid gland was observed to be enlarged. Questions What is the most likely diagnosis of this individual's disorder? What mechanisms regulate the production and release of serum T, and TSH? What other conditions can lead to an increase in serum TSH levels?
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