what are Lethal effects of homozygosity for a deletion

Q: What is the difference in meaning between the terms geneticrecombination and crossing over?

A: Genetics is the branch of biology which deals with genes, heredity, and genome in the organism.…

Q: What does an extra chromosome 16 mean?

A: Chromosomes, the physical carriers of genes, are the microscopic thread like structures in which the…

Q: Please write in digital format Define the following terms: a) Triploid b) Monosomic c) Trisomic d)…

A: Normal cell has a diploid number of chromosomes. Each cell has 23 pairs of chromosomes out of which…

Q: A type AB mother and type AB father will have offspring of what possible genotypes? ___________

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: For a couple, what is the significance of knowing chromosomal aberrations?

A: Chromosomes are thread-like structures present inside the nucleus of the cell. They are made up of…

Q: . If the G locus were 50 or more map units from the centromere, what types and proportions of…

A: Tetraploid means the the species has 4 copies of the genes present ie two diploid gametes would meet…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XO with…

A: The male sex-determining gene in human is termed as the sex determining region Y (SRY) gene.…

Q: How do translocations in which no genetic information is lost or gained produce phenotypic effects?

A: Translocation is caused Due to separation of a chromosome segment and its union to a nonhomologous…

Q: What is the karyotypefound in Down syndrome?

A: During the most recent years, Down disorder has been the focal point of uncommon consideration. Down…

Q: In general, why do changes in chromosome structure or numbertend to affect an individual’s…

A: Chromosome is a compact structure of a DNA molecule wrapped around some proteins. It is generally…

Q: In a cross between an individual with Huntington disease and an unaffected individual, what are the…

A: Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional…

Q: In a two factor cross, the longest possible map distance is 50 map units.  Explain why this is…

A: By finding the recombination frequencies of many gene pairs, we can make genetic or linkage maps. By…

Q: A type AB mother and type AB father will have offspring of what possible phenotypes? ___________

A: Multiple alleles refer to the phenomenon in which there is the occurrence of more than two alleles…

Q: Why can a person carrying a translocation be normal except for theinability to have children?

A: Translocation is a hereditary change were a piece of one chromosome servers and connects to another…

Q: A B C genotype locus phenotype

A: Gene The gene is the unit of genetic information that controls a specific aspect of the phenotype.…

Q: Define heterozygous condition for a gene.

A: Introduction: A gene is the basic unit of heredity. It is a sequence of nucleotides present on DNA…

Q: This is a typical pedigree for a family that carries neurofibromatosis. Is individual I-2 most…

A: Pedigree analysis can help to determine genotypes, identify phenotypes, and predict how a trait will…

Q: what are 9 Phenotypic consequences of deletion andduplication heterozygosity.?

A: Deletion and duplication are the processes which results in chromosomal abnormalities. These are…

Q: A man who is a carrier of a translocated 15/21 chromosome marries a genotypically normal woman. a.…

A: The condition is termed Robertsonian translocation.  Explanation: Every individual has his / her…

Q: From this pedigree is it dominant or recessive. Is ur autosomal or sex-linked?

A: Pedigree is define a diagrammatic representation of the individuals of a family for a particular…

Q: a) What is the chromosomal abnormality associated with Fragile-X Syndrome?   b) What is the…

A: Fragile X syndrome is a genetic condition which causes many problems in development.

Q: Why must the carrier of a genetic disease be heterozygous?

A: Homozygous means a person carries two identical pair of the gene whereas heterozygous means the…

Q: Crossing-over is all of the following EXCEPT

A: The exchange of genetic material between non-sister chromatids of homologous chromosomes is called…

Q: Is this pedigree dominant or recessive. Which best defines this pedigree Autosomal or sex-linked?

A: Introduction :-  A pedigree is a diagram of family history that uses standardized symbols for…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XX with…

A: The sex-determining region Y (SRY) is located on the short branch of the Y chromosome, which…

Q: Explain why unequal crossing over always produced a duplication and deletion at the same time, not…

A: Crossing over occurs in the first division of meiosis at this stage each chromosome has replicated…

Q: What causes nondisjunction?

A: Chromosome is the package of densely packed chromatin fibres with DNA and histone proteins. In…

Q: Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the…

A: The human sex is determined at the time of fertilization in the fallopian tube of the female…

Q: If the G locus were 50 or more map units from the centromere, what types and proportions of gametes…

A: Recombination in terms of genetics describes the process that explains the exchange of genetic…

Q: Explain why autosomal aneuploidy is generally more deleterious than aneuploidy for sex chromosomes.

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: If the G locus were 50 or more map units from the centromere, what types and proportions of gametes…

A: Introduction Recombination:- It is a process by which pieces of DNA are broken and recombined to…

Q: What is incomplete penetrance and what causes it?

A: Introduction  Any gene have two alleles pairs viz. Dominant or Recessive. The allele which gets…

Q: What is crossing over frequency?

A: Crossing over occurs during Prophase (diplotene stage) of meiosis-I and plays a key role in genetic…

Q: CdLS is usually caused by new mutation in oneparent’s gamete. Why?

A: The changes in the sequence of nucleotides are called mutations. The agents that cause mutations are…

Q: If genes a and b are 30 m.u. apart, what percentage of the gametes produced by an AaBb individual…

A: In a allele the distance between two gene a and b is 30 map unit. That's mean the recombinant…

Q: Why Phenotypes may show variations in penetrance and expressivity?

A: Genetics is a branch of science that deals with the study of genes, heredity, and genetic variation…

Q: What is inversion heterozygote?

A: Inversion is a chromosomal rearrangement when a segment of chromosome breaks and then rejoins in…

Q: What are The effects of random events on penetrance and expressivity?

A: Genotype- It is the set of genes that we have inherited from our parents and will pass on these…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXY with…

A: A gene is a unit of genetic material present within the DNA (deoxyribonucleic acid). Each gene…

Q: What some ways that incomplete penetrance can occur? Give at least two possible ways on why it…

A: Penetrance refers to the proportion of people with a particular genetic change (such as a mutation…

Q: What is heterozygous variant?

A: The term heterozygous variant belongs to a subdivision of biology, genetics. Genetics is the study…

Q: What types of chromosomal disorders are easily seen with a karyotype?

A: KARYOTYPE:- It is the complete set of chromosomes of an individual used to check for any…

Q: what is the probability that a couple (both heterozygous for the same recessive mutation) will have…

A: “Homozygous defect” takes place If the type of “deleterious mutation” is the same in both copies of…

Q: How does nondisjunction lead to abnormalities in chromosome number? Describe two types of genetic…

A: The failure of chromosome to seperate properly  during mitosis or meiosis is called nondisjunction…

Q: Two phenotypically unaffected parents produce two children withfamilial Down syndrome. With regard…

A: Chromosomal aberrations include changes in the structure and number of chromosomes. Thus, meiosis…

Q: Why is trisomy 21 not lethal?

A: Trisomy 21 an equivalent name for Down syndrome is the most common genetic disorder. It causes both…

Q: based on fig 1. Is this karyotype a male or female? Is there a chromosomal disorder? What type of…

A: Karyotype --  is complete collection of chromosomes of a person it may be a male or female karyotype…

Q: What is a crossing over, and what is the purpose of it?

A: The cell cycle is the orderly series of events allowing a cell to grow and divide forming daughter…

Substance Abuse

Substance abuse refers to the use of illegal drugs in excessive quantities, as well as the misuse of legal substances such as prescription or over-the-counter pharmaceuticals or alcohol for purposes other than those intended. Drug addiction, also known as substance use disorder, is a disease that affects the brain and behavior of a person. It leads to a failure to control the use of any drug or prescription, legal or illegal.