Use the Following information to answer questionse EIA results are recorded as optical-density (OD) ratios. The OD ratio is the ratio of absorbance of the tested sample to the absorbance of a control sample. The greater the OD ratio, the more "positive" is the test result. The EIA, as with most other screening tests, is not perfect; there is some overlap of optical-density ratios of samples that are actually antibody positive and those that are actually antibody negative. This is illustrated in the following figure: Hypothetical distribution of results on an EIA for HIV, by actual antibody status In terms of sensitivity and specificity, what happens if you lower the cut-off from "A" to "C"? Actualy without antbody Actualy have antbody In terms of sensitivity and specificity, what happens if you raise the cut-off from "A" to "B"? OD Rato Mumber of persons
Use the Following information to answer questionse EIA results are recorded as optical-density (OD) ratios. The OD ratio is the ratio of absorbance of the tested sample to the absorbance of a control sample. The greater the OD ratio, the more "positive" is the test result. The EIA, as with most other screening tests, is not perfect; there is some overlap of optical-density ratios of samples that are actually antibody positive and those that are actually antibody negative. This is illustrated in the following figure: Hypothetical distribution of results on an EIA for HIV, by actual antibody status In terms of sensitivity and specificity, what happens if you lower the cut-off from "A" to "C"? Actualy without antbody Actualy have antbody In terms of sensitivity and specificity, what happens if you raise the cut-off from "A" to "B"? OD Rato Mumber of persons
Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
18th Edition
ISBN:9780079039897
Author:Carter
Publisher:Carter
Chapter10: Statistics
Section10.5: Comparing Sets Of Data
Problem 14PPS
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![Use the Following information to answer questionss
EIA results are recorded as optical-density (OD) ratios. The OD ratio is the ratio of absorbance of the tested sample to the
absorbance of a control sample. The greater the OD ratio, the more "positive" is the test result. The EIA, as with most other
screening tests, is not perfect; there is some overlap of optical-density ratios of samples that are actually antibody positive and
those that are actually antibody negative. This is illustrated in the following figure:
Hypothetical distribution of results on an EIA for HIV,
by actual antibody status
In terms of sensitivity and specificity, what happens if you lower
the cut-off from "A" to "C"?
Actualy
without
antibody
Actualy
In terms of sensitivity and specificity, what happens if you raise
have
antbody
the cut-off from "A" to "B"?
CA
OD Ratio
Establishing the cutoff value to define a
positive test result from a negative one is
somewhat arbitrary. You initially decide that
optical density ratios greater than "A" on
the above figure are positive.
suOGod o oqunN](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F24c8158d-03bb-49f0-a627-684eab2f58c9%2F55409a04-ed14-4419-9f81-778bad59a7be%2Fci79osi_processed.png&w=3840&q=75)
Transcribed Image Text:Use the Following information to answer questionss
EIA results are recorded as optical-density (OD) ratios. The OD ratio is the ratio of absorbance of the tested sample to the
absorbance of a control sample. The greater the OD ratio, the more "positive" is the test result. The EIA, as with most other
screening tests, is not perfect; there is some overlap of optical-density ratios of samples that are actually antibody positive and
those that are actually antibody negative. This is illustrated in the following figure:
Hypothetical distribution of results on an EIA for HIV,
by actual antibody status
In terms of sensitivity and specificity, what happens if you lower
the cut-off from "A" to "C"?
Actualy
without
antibody
Actualy
In terms of sensitivity and specificity, what happens if you raise
have
antbody
the cut-off from "A" to "B"?
CA
OD Ratio
Establishing the cutoff value to define a
positive test result from a negative one is
somewhat arbitrary. You initially decide that
optical density ratios greater than "A" on
the above figure are positive.
suOGod o oqunN
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