Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?

Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?

Name: Though an individual with abberations such as Robertsonian translocati
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Description: Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriag

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 16QP: Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies...

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Assume that a meiotic-nondisjunction event causes trisomy 8 in a newborn. If two of the three copies of chromosome 8 are absolutely identical, at what point during meiosis did the nondisjunction event take place?
A diploid (2n) trihybrid individual with the genotype EeFfGg can make eight genetically different gametes. Loci E/e and F/f are on chromosome 1 and locus G/g is on chromosome 2. Explain how a gamete containing the alleles e, f and g may be produced by meiosis. Refer specifically to meiotic events occurring during Prophase I, Metaphase I, Anaphase I and Anaphase II. (NB: remember to refer to the organism above).
Meiosis is characterized by the pairing of homologouschromosomes during prophase I. In many species, an elaboratestructure called the synaptonemal complex forms betweenhomologues. During this pairing, homologues may exchangechromosomal material at sites called chiasmata. In meiosis I, thehomologues separate from each other, reducing the chromosomenumber to the haploid state (thus the reductive division). It isfollowed by a second division without replication, during whichsister chromatids become separated. The result of meiosis I and IIis four haploid cells. If sister chromatids separated at the first division, would meiosis still work?
During metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes (2n=4) . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is 22 or 4.For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is 23 or 8. In an organism with a haploid number of 7, how many possible combinations of maternal and paternal chromosomes can occur in its gametes? a. 72=49 b. 27=128 c.17=1 d. 214=16 384
During metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is , or .For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is , or . In an organism with a haploid number of , how many possible combinations of maternal and paternal chromosomes can occur in its gametes? Select one: a. 72=49 b. 27=128 c.17=1 d. 214=16 384
In fruit flies, chromosomal crossing over does not occur in meiosis in males, whereas crossing over does occur in meiosis in females. In fruit flies that are heterozygous at many genes (i.e. many maternal and paternal versions of the genes differ), at what stage would cells no longer be heterozygous for any gene during the process of meiosis? a)After the second meiotic division in males, and after the first meiotic division in females. b)After the second meiotic division in both males and females. c)After the first meiotic division in both males and females. d)After the first meiotic division in males, and after the second meiotic division in females.
Which is the type ofgamete produced by aheterozygous individual?What is the genotypicalproportion of these gametes?
If nondisjunction occurs in humans for one pair of homologous chromosomes during meiosis I. The other pairs segregate normally. a) Will any normal gametes result? b) How many chromosomes will each human gametehave? If nondisjunction occurs in humans for sister chromatids during meiosis II. The other pairs segregate normally. a) Will any normal gametes result? b) How many chromosomes will each human gamete have?
If nondisjunction occurs in humans for one pair of homologous chromosomes during meiosis I. The other pairs segregate normally. a) Will any normal gametes result? b) How many chromosomes will each human gamete have? If nondisjunction occurs in humans for sister chromatids during meiosis II. The other pairs segregate normally. a) Will any normal gametes result? b) How many chromosomes will each human gamete have?
A diploid organism produces four gametes from one parent cell through the process of meiosis. Two gametes are found to have 7 chromosomes and two gametes are found to have 5 chromosomes. A) Is this the expected number of chromosomes that would be found in each gamete following a normal cycle of meiosis? If yes, explain why. If no, explain why not and describe how the gamete situation described above occurred. B) Determine the number of homologous chromosome pairs that the original parent cell contained, before meiosis began. Explain how you determined this value.
Suppose that meiosis occurs in the transient diploid stageof the cycle of a haploid organism of chromosome number n. What is the probability that an individual haploidcell resulting from the meiotic division will have a complete parental set of centromeres (that is, a set all fromone parent or all from the other parent)?
An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Draw the pairing arrangement of these chromosomes in prophase I of meiosis.