Answered: The following two sequences represent…

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter4: Cell Structure

Section: Chapter Questions

Problem 43CTQ: Pathogenic E. coil have recently been shown to degrade tight junction proteins during infection. How...

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Question

The following two sequences represent the same gene from two different species: Assume that all changes in the third position are synonymous and all in the first and second positions are nonsynonymous.

a) How many synonymous sites (positions) are there in the gene?

b) How many nonsynonymous sites (positions) are there in the gene?

c) How many synonymous substitutions are there between species?

d) How many nonsynonymous substitutions are there between species?

e) What is the dN/dS ratio?

f) What does the dN/dS ratio tell you about the evolution of this sequence?

Finally, It has been hypothesized that population size affects genome size. What is the proposed relationship? How can it be explained?

Arg Ala
Ser
Gly
Thr
Arg
Thr Pro Ser
Arg
Arg
Thr Val Leu Leu
CGG GCA TCA GGG ACT CGA ACG CCC TCA CGG CGG ACC GTT CTC CTT
CGA GCC TCG GGA ACC CCA ACG CCC TCA GGG CGC TCC GTC CTG CTT
Arg
Ala
Ser
Gly
Thr
Pro
Thr
Pro Ser
Gly
Arg
Ser Val Leu Leu

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