Sodium hydroxide is used to partially neutralize sulfuric acid from the one-pot Friedel-Crafts and amide hydrolysis reactions. Which bases can deprotonate a phenol that has a pKa of 10.0? Consider the pKa of the conjugate acid of each base. OH NaH NaOH Na2CO3 NaHCO3

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter18: Carboxylic Acids
Section: Chapter Questions
Problem 18.21P
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Sodium hydroxide is used to partially neutralize sulfuric acid from the one-pot
Friedel-Crafts and amide hydrolysis reactions. Which bases can deprotonate a
phenol that has a pKa of 10.0? Consider the pKa of the conjugate acid of each base.
OH
NaH
NaOH
Na2CO3
NaHCO3
Transcribed Image Text:Sodium hydroxide is used to partially neutralize sulfuric acid from the one-pot Friedel-Crafts and amide hydrolysis reactions. Which bases can deprotonate a phenol that has a pKa of 10.0? Consider the pKa of the conjugate acid of each base. OH NaH NaOH Na2CO3 NaHCO3
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