Regarding TLC plates: a) When spotting a TLC plate, are small spots or large spots better? Or does the size of the spots not matter? b) Do separation of compounds on a TLC plate depends primarily on polarity, boiling point, molecular weight, melting point, or density?

Chemical Principles in the Laboratory
11th Edition
ISBN:9781305264434
Author:Emil Slowinski, Wayne C. Wolsey, Robert Rossi
Publisher:Emil Slowinski, Wayne C. Wolsey, Robert Rossi
Chapter2: Resolution Of Matter Into Pure Substances, I.paper Chromatography
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Regarding TLC plates: a) When spotting a TLC plate, are small spots or large spots better? Or does the size of the spots not matter? b) Do separation of compounds on a TLC plate depends primarily on polarity, boiling point, molecular weight, melting point, or density?
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