Rank the reactivity of the compounds below toward nucleophilic acyl substitution by writing the compounds' letters in the proper blanks in the box below. HN. CI Br CH3 CH3 A C D E rank compounds for acyl substitution reactivity

Q: CH3 + NAOH CH CH CH CH A) II B)I C) II D) IV Which carbon atoms are most susceptible to nucleophilic…

A: Given, reaction is the acid-base reaction. Electron withdrawing groups like carbonyl group (CO)…

Q: Which of the following statements about ethanethiol (CH3CH2SH) is(are) correct? Ethanethiol will be…

A: Ethanethiol in presence of NaOH: CH3CH2SH+NaOH→CH3CH2S-+Na++H2OEthanethiol…

Q: Vhich of the following functional groups are present in 2-hydroxy-1,2-diphenylethan1-one? n ester O…

A: The name of the compound given is 2-hydroxy-1,2-diphenyl than-1-one.

Q: Rank the following esters from most reactive to least reactive in the first slow step of a…

A: First the reactivity order of given compounds from most reactive to least reactive in the first slow…

Q: Below is a short reaction sequence. Provide the structure of the two missing organic compounds. NaOH…

A: If the base is alc.NaOH then it undergoes elemination reaction results in the formation of highly…

Q: Rank the following compounds from most reactive to least reactive in an electrophilic aromatic…

A: Electrophilic aromatic substitution: In an organic reaction in which an electrophile replaced an…

Q: Other Phenol Derivatives Derivatives are prepared to improve the properties of its parent. I.…

A:

Q: In reactions with an aldehyde or ketone to form an imine or an enamine (Section 16.8)

A: Solution :      Aldehyde or ketone shows dehydration reaction with an amine to form imines. Imines…

Q: Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by…

A: The major drawback of the method in which primary amine synthesis is done by using the reaction of…

Q: Explain why carboxylic acids do not undergo nucleophilic acyl substitution reactions with amines.

A: A chemical species which has high electron density or a lone pair of electrons, by using which it…

Q: consider the following reaction of a carbonyl to an alkene "CH2 P-Ph Ph Ph CH2 Phosphonium ylide…

A:

Q: When butanoic acid and 18O-labeled methanol react under acidic conditions, what compounds are…

A: The given reaction between butanoic acid and methanol forms methyl butanoate and water. As oxygen…

Q: Which of the following is the appropriate reactants for the synthesis of pyrrole derivative below.…

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Q: (II) Provide the IUPAC name for the following carbonyl compounds. PHCH2CH(CH3)CH2CH2CHO…

A:

Q: B) Benzene to N-methyl-3-phenyl propanamide Он c)

A: The synthesis of the following is:

Q: Identify the products obtained by the hydrolysis of the given compound. оо -COC- Select one: one…

A:

Q: Which of the following will NOT produce a carboxylic acid or carboxylate ion?     2-butene + O3…

A: Answer: A.  2-Butene with ozone will form the ozonide that on treating dimethyl sulfide will give…

Q: 'N' CI

A: The better the leaving group, higher the reactivity of carboxylic acid derivative. Or The higher the…

Q: Label each compound as more or less reactive than benzene in electrophilic aromatic substitution.

A: SOLUTION: Step 1: The substituents on the benzene determine the reactivity of benzene. The reaction…

Q: What is the problem with running the following reaction? NH2 HNO3 H2SO4 It will result in multiple…

A:

Q: Consider the following reaction to form compound C. OH H3C cat. Ph H OCN В Ph A a) Indicate the most…

A: More electrophilic centre will react with cat. Cyanide, Because CN- is a nucleophile.

Q: Under certain conditions interacts with sodium nitrite: A. Resorcinol B. Nicotinic acid C. Butadion…

A: A question based on molecule that is to be accomplished.

Q: Q10:- Explain how Esters are more reactive than amides in nucleophilic acyl substitution reactions.

A: The structure of ester and amide are as follows:

Q: Write reactions of 2-oxopropanoic acid with the following reagents: CH3NH2; NaBH4.

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Q: Ph. OTMS TBAF THE benzyne

A: Given reactions are example of Diels-Alder reaction.  Which is 4+2 cycloaddition reaction  Diene and…

Q: Draw the structure of A, an intermediate in the synthesis of the antipsychotic drug risperidone.…

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Q: Rank the attached compounds in order of increasing basicity.

A: Basicity of the aniline depends on the substituents. If electron withdrawing groups  are presesnt…

Q: t. acetic acid + PCl; u. pent-3-en-2-one + methanol v. butanone + 2 equivalents of methylamine and…

A:

Q: Which of the following bases most favors elimination over substitution? (CH3)3CO- O H2O CH30- CN-

A: More basic  anion most favors  elimination reaction over substitution.

Q: Arrange the following compounds in order of decreasing reactivity towards hydrolysis. H2N. H3CO NAI…

A: A question based on reactivity towards hydrolysis reaction, which is to be accomplished.

Q: 13:58 ll 4G 5 © T Ô 2. What is the correct IUPAC name for the following compound? CH3 H2N" ČH3…

A: Here we have to write correct IUPAC name of above given compound-

Q: Identify the type of reaction for the following: formation of (S)-2-butanol from (S)­-2-bromobutane…

A: Given is the reaction of bromo alkane which form alcohol with same stereochemistry. First SN2…

Q: Q3\ The pKa of p-cyclopropylbenzoic acid is 4.45. Is cyclopropylbenzene likely to be more reactive…

A:

Q: Draw the structure of A, an intermediate in the synthesis of the antipsychotic drug risperidone.…

A: The structure of A has to be drawn

Q: Rank the following carboxylic acid derivatives in decreasing order (most to least) of reactivity…

A: Reactivity of the carboxylic acid derivatives can be based on the ability of the leaving group or on…

Q: What alkyl halide is needed to prepare each 1° amine by the Gabriel synthesis?

A: Introduction: Gabriel Phthalimide synthesis is the forms the primary amine from primary alkyl…

Q: 1. Which is the strongest base? „NH2 „NH2 NH *NH2 а. с b, ON" d. C. 2. Which of the following…

A: Given

Q: Which one of the following carboxylic acid derivatives can undergo nucleophilic acyl substitution…

A: Nucleophilic acyl substitution (acyl transfer reaction) occurs by a two-step mechanism. First,…

Q: 1D.) In the ¹H-NMR spectra of carboxylic acids, the carbocylic acid proton bonded the oxygen atom…

A:

Q: Classify the conversion of A to B as a substitution, elimination, or addition. B can be converted to…

A: Substitution reaction is the reaction involves the displacement of one group by other. Example:…

Q: Rank the following compounds from most reactive to least reactive in an electrophilic aromatic…

A: The reaction in which an electrophile gets substituted to the benzene ring in place of H+ is known…

Q: The intermediote in the bromination of benzenesulfonic acid is SOH SOH H. Br SOH H Br OH SOH H. Br…

A: correct option is opotion 2

Q: 48. Neutral iron (III) chloride is uscd to distinguish between phenols and non-phenolic aromatic…

A: Given 48 First Statement : Neutral Iron(III) chloride is used to distinguish between phenols and…

Q: Identify the hydrolysis product of the cyclic enamine below 1) H30* 2) NaOH Ph The compound below Ph…

A: Option c is correct

Q: 2. Oxybenzone and 2-ethylhexyl-p-methoxycinnamate are UV absorbing compounds used in sunscreens.…

A:

Q: A key step in the synthesis of the narcotic analgesic meperidine (trade name Demerol) is the…

A: a) Please see the attached picture. b) Acidic Ethanolysis Please see: Analgesics by R.S. Vardanyan,…

Q: Which one of the following compounds give racemic mixture when treated with NaOH (aq)? A…

A: To obtain racemic mixture we know that the reaction should proceed through SN1 reaction mechanism.…

Q: of 1. conc. HBr HO. Br 2. (Ph),C-OH HCI (Ph)3C-CI H20 f = Sy1 Nucleophilic substitution d = E1…

A: The two reactions given are,

Q: Provide the reagents necessary to convert 3-methyl-2-butanol to 2-bromo-3-methylbutane. CHOOSE FROM…

A: Answer:-              PBr3 is the reagents necessary to convert 3-methyl-2-butanol to…