Question:- I have a case (not real btw) of a 25 year old female who was admitted to the hospital with a history of persistent fever that did not respond to amoxicillin or acetaminophen or ibuprofen. She was a resident of the Philippines who had been travelling in Europe for the previous 11 days. On physical examination, she was febrile, had an enlarged liver, abdominal pain, and an abnormal urinalysis. After isolation and cultivation, the infectious agent was found to exist as Gram-negative, facultative anaerobic rods. The organism could fermenter and was oxidase negative. It possessed lipopolysaccharide consisting of outer somatic O polysaccharide, core polysaccharide (common antigen) and lipid A (endotoxin) What is the infectious agent and what further tests could you do to confirm the preliminary identification?
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Question:-
I have a case (not real btw) of a 25 year old female who was admitted to the hospital with a history of persistent fever that did not respond to amoxicillin or acetaminophen or ibuprofen. She was a resident of the Philippines who had been travelling in Europe for the previous 11 days. On physical examination, she was febrile, had an enlarged liver, abdominal pain, and an abnormal urinalysis.
After isolation and cultivation, the infectious agent was found to exist as Gram-negative, facultative anaerobic rods. The organism could fermenter and was oxidase negative. It possessed lipopolysaccharide consisting of outer somatic O polysaccharide, core polysaccharide (common antigen) and lipid A (endotoxin)
What is the infectious agent and what further tests could you do to confirm the preliminary identification?
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- A 56-year-old man complained of progressive fatigue and malaise. His physical examination was generally satisfactory, with a pulse of 90 beats per minute, and multiple lymphadenopathy and hepatomegaly. No bacteria were found in cerebrospinal fluid smears of lumbar puncture, but a flagellum, elongated nucleus with blue and red cytoplasm were found in the blood by Giemsa staining of thin blood smears. The family reported that the patient had been engaged in transportation business in Africa for many years. 1. What do you think is the most likely disease for this patient? Malaria Dengue fever African sleeping disease Toxoplasma encephalitis Bacterial meningitis 2. What do you think is the most likely pathogen for this patient? Plasmodium vivax Toxoplasma gondii Plasmodium falciparum Plasmodium malariae Trypanosoma brucei gambiense 3. What do you think is the most direct basis for the diagnosis of the pathogen? From Africa Fatigue Hepatomegaly Special structure was found on blood…Mr. Hooke a 35 y/o male presented himself in the clinic complaining of shortness of breath and having fevers for the past few weeks. He is known to be infected with HIV for almost 2 years already. He returns to HIV clinic at different intervals for follow-up. He has been on stable antiretroviral therapy consisting on didanosine, stavudine, and indinavir for the past year. Patient history revealed that he is unsure about his immunization status, and thinks he got them as a child. Physical Examination as follows: General: thin, anxious, acutely ill-appearing, young white man with tachypnea Neck/LN: slight cervical lymphadenopathy, thyroid normal Lungs/Thorax: CTA, slight axillary lymphadenopathy Labs Chest X-ray: Bilateral subtle infiltrates Bronchoscopy with BAL: positive for the presence of a unicellular eukaryote, a yeast-like fungus Assessment: breakthrough opportunistic infection question: What drug, dosage form, schedule, and duration of therapy are best for treating this…Mr. Hooke a 35 y/o male presented himself in the clinic complaining of shortness of breath and having fevers for the past few weeks. He is known to be infected with HIV for almost 2 years already. He returns to HIV clinic at different intervals for follow-up. He has been on stable antiretroviral therapy consisting on didanosine, stavudine, and indinavir for the past year. Patient history revealed that he is unsure about his immunization status, and thinks he got them as a child. Physical Examination as follows: General: thin, anxious, acutely ill-appearing, young white man with tachypnea Neck/LN: slight cervical lymphadenopathy, thyroid normal Lungs/Thorax: CTA, slight axillary lymphadenopathy Labs Chest X-ray: Bilateral subtle infiltrates Bronchoscopy with BAL: positive for the presence of a unicellular eukaryote, a yeast-like fungus Assessment: breakthrough opportunistic infection question: Could any of the patient’s problems have been caused by drug therapy?
- Mr. Hooke a 35 y/o male presented himself in the clinic complaining of shortness of breath and having fevers for the past few weeks. He is known to be infected with HIV for almost 2 years already. He returns to HIV clinic at different intervals for follow-up. He has been on stable antiretroviral therapy consisting on didanosine, stavudine, and indinavir for the past year. Patient history revealed that he is unsure about his immunization status, and thinks he got them as a child. Physical Examination as follows: General: thin, anxious, acutely ill-appearing, young white man with tachypnea Neck/LN: slight cervical lymphadenopathy, thyroid normal Lungs/Thorax: CTA, slight axillary lymphadenopathy Labs Chest X-ray: Bilateral subtle infiltrates Bronchoscopy with BAL: positive for the presence of a unicellular eukaryote, a yeast-like fungus Assessment: breakthrough opportunistic infection Case Study Questions: Aside from HIV, what is your diagnosis? Support your clinical diagnosis. Could…Mr. Hooke a 35 y/o male presented himself in the clinic complaining of shortness of breath and having fevers for the past few weeks. He is known to be infected with HIV for almost 2 years already. He returns to HIV clinic at different intervals for follow-up. He has been on stable antiretroviral therapy consisting on didanosine, stavudine, and indinavir for the past year. Patient history revealed that he is unsure about his immunization status, and thinks he got them as a child. Physical Examination as follows: General: thin, anxious, acutely ill-appearing, young white man with tachypnea Neck/LN: slight cervical lymphadenopathy, thyroid normal Lungs/Thorax: CTA, slight axillary lymphadenopathy Labs Chest X-ray: Bilateral subtle infiltrates Bronchoscopy with BAL: positive for the presence of a unicellular eukaryote, a yeast-like fungus Assessment: breakthrough opportunistic infection Case Study Questions: 1.Aside from HIV, what is your diagnosis? Support your clinical diagnosis.15 year old African American male presents with his mother to the ER where you are the physician assistant helping the ER attending in a very busy rural hospital. He is complaining of abdominal pain for one day and nausea with vomiting. His mother reports a fever and malaise. He has no significant medical history but his mother is concerned that he may have the "kissing disease" as he has a boy friend who had mononucleosis six months ago and she does not approve of him anyway. He describes the abdominal pain as sharp and points to his umbilical region. He ranks it 10/10 on a 1-10 scale at its worse and he says it gets worse with sudden movements or if he sits up too quick or laughs. He is not on any medications and his vital signs are normal except for a temperature of 101 degrees Fahrenheit. On examination he looks sick and his skin is clammy to the touch. Heart and lung examination is unremarkable. Abdominal examination shows good bowel sounds and umbilical tenderness and…
- 5 year old African American male presents with his mother to the ER where you are the physician assistant helping the ER attending in a very busy rural hospital. He is complaining of abdominal pain for one day and nausea with vomiting. His mother reports a fever and malaise. He has no significant medical history but his mother is concerned that he may have the "kissing disease" as he has a boy friend who had mononucleosis six months ago and she does not approve of him anyway. He describes the abdominal pain as sharp and points to his umbilical region. He ranks it 10/10 on a 1-10 scale at its worse and he says it gets worse with sudden movements or if he sits up too quick or laughs. He is not on any medications and his vital signs are normal except for a temperature of 101 degrees Fahrenheit. On examination he looks sick and his skin is clammy to the touch. Heart and lung examination is unremarkable. Abdominal examination shows good bowel sounds and umbilical tenderness and…A 48-year-old businessman, presents at the emergency room with a 12-day history of headache, myalgia, nausea, and vomiting. Patient history reveals that the patient is a consulting engineer for the tropical area. On his latest trip, he failed to take his prophylaxis for malaria. According to his general physician’s records, all his immunizations are up to date. His fever was 39°C at the time of initial examination, but alternated with periods of extreme cold and cyanosis. A complete blood count was ordered, along with parasite examination and urinalysis. What parasite do you suspect? Which morphological factor will be important in deciding the species of this organism? Which morphological form you may observe in the peripheral blood of this patient? How did the patient contract this parasitic infection? Why this species can cause much more serious result than other species among this organism? Please list name of three parasites that lead to anemia as the main symptoms, and their…This is homework not a test! From NTSA case study https://static.nsta.org/case_study_docs/case_studies/cystic_fibrosis.pdf Please help with questions 2, 3 and 4 of part four 2. "The successful use of gene therapy to cure SCID syndrome (2000) is hoped to be a permanent cure for those patients because a good copy of the problem gene was inserted into the patients' blood stem cells in the bone marrow (hematopoietic stem cells). Once white blood cells enter the blood stream they have a limited life span, on the order of a few week to months. The blood stem cells are the cells that create more white blood cells to replace those that are lost. If the gene was only inserted into the circulating mature white blood cells, the patient would only be temporarily cured until those cells were used up or died." The current gene therapy approaches to cure CF involve inserting a functional CFTR gene into the mature epithelial cells of the lungs. In light of the preceding paragraph, do you think that…
- Patient X was rushed to a nearby hospital in Tuguegarao City after experiencing severe abdominal pain, persistent vomiting, marked change in temperature going from fever to hypothermia, restlessness, cold, clammy skin, and rapid, weak pulse. In addition, Patient X noted that she experienced high bouts of fever during the first week but has subsided. Small red spots or purple splotches can be seen on her skin, and she tested positive on the tourniquet test. According to her travel history, she recently visited Aklan and Negros Occidental Answer the following questions:4. Which of her symptoms indicate early signs of shock? Which of her symptoms point to hemorrhagic manifestations?5. Enumerate laboratory methods that can be used to diagnose the disease or detect the virus.6. How is the disease treated and controlled/prevented?Patient X was rushed to a nearby hospital in Tuguegarao City after experiencing severe abdominal pain, persistent vomiting, marked change in temperature going from fever to hypothermia, restlessness, cold, clammy skin, and rapid, weak pulse. In addition, Patient X noted that she experienced high bouts of fever during the first week but has subsided. Small red spots or purple splotches can be seen on her skin, and she tested positive on the tourniquet test. According to her travel history, she recently visited Aklan and Negros Occidental Answer the following questions:1. Which disease is characterized by the symptoms experienced by Patient X? Correlate her medical information and travel history to the disease.2. Explain the pathology of the disease.3. Which virus could have caused the disease? How did she contract the virus?4. Which of her symptoms indicate early signs of shock? Which of her symptoms point to hemorrhagic manifestations?5. Enumerate laboratory methods that can be used…Patient X was rushed to a nearby hospital in Tuguegarao City after experiencing severe abdominal pain, persistent vomiting, marked change in temperature going from fever to hypothermia, restlessness, cold, clammy skin, and rapid, weak pulse. In addition, Patient X noted that she experienced high bouts of fever during the first week but has subsided. Small red spots or purple splotches can be seen on her skin, and she tested positive on the tourniquet test. According to her travel history, she recently visited Aklan and Negros Occidental. Answer the following questions: (Provide reference and in-text citation) 1. Which disease is characterized by the symptoms experienced by Patient X? Correlate her medical information and travel history to the disease. 2. Explain the pathology of the disease. 3. Which virus could have caused the disease? How did she contract the virus? 4. Which of her symptoms indicate early signs of shock? Which of her symptoms point to hemorrhagic manifestations? 5.…