QUESTION 34 Which of the following events does NOT occur during ERAD (ER-associated degradation)? OA. Chaperone-mediated attempts at protein folding OB. Degradation of misfolded proteins by the proteasome OC. Targeting of mis-folded proteins to the nucleus OD. Repeated attempts at protein folding QUESTION 35 Which of the following statements regarding COPII vesicles trafficking between the ER and the Golgi is NOT correct? OA. Uncoated vesicles fuse with the cis-Golgi. OB. The vesicle enclosed in a COPII coat fuses with the cis-Golgi. OC. The COPII vesicles lose the COPII coat before reaching the Golgi. OD. COPII-coated vesicles bud off from the RER. QUESTION 36 Which phenotype would you expect to see in cells that contain a defective Rab GTPase that cannot be activated on the inner surface plasma membrane? OA. The cell would lack secretory vesicles. OB. No phenotype OC. The cell would have an excess of secretory vesicles within the cytoplasm and defective secretion. OD. The cell would have an excess of secretory vesicles bound to cytoplasmic face of the trans Golgi network.

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Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.