Propranolol binds to beta-adrenergic receptors with a Kj of 8.9 x 10-9M. What concentration of propranolol would be required to achieve a 50% reduction in the binding of the receptor agonist isoproterenol if the agonist concentration is 10nM and its dissociation constant for the receptor is 4.8 x 10-8 M?

Propranolol binds to beta-adrenergic receptors with a Kj of 8.9 x 10-9M. What concentration of propranolol would be required to achieve a 50% reduction in the binding of the receptor agonist isoproterenol if the agonist concentration is 10nM and its dissociation constant for the receptor is 4.8 x 10-8 M?

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter4: Acids And Bases

Section: Chapter Questions

Problem 4.18P: If the G for a reaction is 4.5 kcal/mol at 298 K, what is the Keq for this reaction? What is the...

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A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…
A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…
A 35 year old male was taken to the hospital with excruciating pain in the lower abdominal area. It was discovered that this patient drank no more than half a glass of water each day over the past week, while drinking at least three cups of black tea on the same days. Additionally, the patient regularly eats very large quantities of spinach. Upon further analysis, it was determined that the presence of Calcium Iodideand Sodium Oxalate may have led to the pain that the patient was experiencing. Determine whether or not kidney stones could be the probable cause of the lower abdominal pain for this patient by answering the following questions (Be sure to show your work for all parts): Assume that Calcium Iodideand Sodium Oxalate are the starting substances (reactants) in the reaction: a. Write a balanced chemical equation describing the formation of kidney stones, using the information in the case study. b. State the names of the products that are produced from this reaction. c.…
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