Pharmacokinetics of cyclophosphamide

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Pharmacokinetics of cyclophosphamide 

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Step 1

Pharmacokinetics is the term which describes the process that what our body does to a drug when the drug entered our body. It is of 4 stages they are,

 

  1. Absorption of the drug
  2. Metabolism of the drug
  3. Distribution of the drug
  4. Excretion of the drug.
Step 2

Cyclophosphamide is a immunosuppressant commonly used as a chemptherapeutic agent for cancer treatment and is also used in AL amyloidosis and graft-versus host disease.

 

Absorption:  absorption means when a drug is taken orally from the gut it should be absorbed into the body. Bioavailability means if we take 100 mg of a drug if the drug is completely absorbed into the body then we can say that the bioavailability of the drug is 100%. Cyclosphosmide absorption is very rapid it takes just one hour to completely absorb from the gut to the body.

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