Oxygen is transported around the body by the globular protein hemoglobin which contains four Fe2* ions. Hemoglobin is “oxygenated" when coordinated to dissolved oxygen in the blood. This can be simplistically represented by the following equation (where Hb represents one hemoglobin molecule): HЬ (аq) + 40о2 (9) + нь(02)4 (ад) (1) Hemoglobin also readily binds with carbon monoxide (CO). Indeed, hemoglobin has a much higher affinity to CO than O, resulting in significantly stronger hemoglobin binding to CO than to O2. This is a problem because hemoglobin molecules which are coordinated to carbon monoxide are unable to transport oxygen around the body as needed. No more than 2.5% of your body's hemoglobin can be bound to CÓ before health effects become noticeable. The consequence is that even very low partial pressures of CO in the air have physiological implications for humans. нь (ад) + 4Cо (9) + нь(со)4 (аq) (2) Compare and evaluate the relative magnitudes of the equilibrium constant for reaction 1 and reaction 2. The displacement of oxygen bound to haemoglobin with carbon monoxide can be simplistically represented by the following equation: нь02 (ад) + СО (9) + нь(со) (ад) + 02 (9) The equilibrium constant, K, of reaction 3 is ~200 at body temperature. If the ratio [HBCO]/[HbO2] approaches 1, death is probable for humans. Calculate the partial pressure of CO (g) in the air (at equilibrium) that is likely to be fatal? Assume the partial pressure of O2 (g) is 0.20 atm. Hint: Write the equilibrium constant expression for the new reaction presented above. Are there expressions that we can cancel/neglect?
Oxygen is transported around the body by the globular protein hemoglobin which contains four Fe2* ions. Hemoglobin is “oxygenated" when coordinated to dissolved oxygen in the blood. This can be simplistically represented by the following equation (where Hb represents one hemoglobin molecule): HЬ (аq) + 40о2 (9) + нь(02)4 (ад) (1) Hemoglobin also readily binds with carbon monoxide (CO). Indeed, hemoglobin has a much higher affinity to CO than O, resulting in significantly stronger hemoglobin binding to CO than to O2. This is a problem because hemoglobin molecules which are coordinated to carbon monoxide are unable to transport oxygen around the body as needed. No more than 2.5% of your body's hemoglobin can be bound to CÓ before health effects become noticeable. The consequence is that even very low partial pressures of CO in the air have physiological implications for humans. нь (ад) + 4Cо (9) + нь(со)4 (аq) (2) Compare and evaluate the relative magnitudes of the equilibrium constant for reaction 1 and reaction 2. The displacement of oxygen bound to haemoglobin with carbon monoxide can be simplistically represented by the following equation: нь02 (ад) + СО (9) + нь(со) (ад) + 02 (9) The equilibrium constant, K, of reaction 3 is ~200 at body temperature. If the ratio [HBCO]/[HbO2] approaches 1, death is probable for humans. Calculate the partial pressure of CO (g) in the air (at equilibrium) that is likely to be fatal? Assume the partial pressure of O2 (g) is 0.20 atm. Hint: Write the equilibrium constant expression for the new reaction presented above. Are there expressions that we can cancel/neglect?
Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter3: Chemical Reactions
Section: Chapter Questions
Problem 156QRT: Ethanol, C2H5OH, is a gasoline additive that can be produced by fermentation of glucose....
Related questions
Question
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
Chemistry: The Molecular Science
Chemistry
ISBN:
9781285199047
Author:
John W. Moore, Conrad L. Stanitski
Publisher:
Cengage Learning
Chemistry for Engineering Students
Chemistry
ISBN:
9781337398909
Author:
Lawrence S. Brown, Tom Holme
Publisher:
Cengage Learning
Chemistry & Chemical Reactivity
Chemistry
ISBN:
9781337399074
Author:
John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:
Cengage Learning
Chemistry: The Molecular Science
Chemistry
ISBN:
9781285199047
Author:
John W. Moore, Conrad L. Stanitski
Publisher:
Cengage Learning
Chemistry for Engineering Students
Chemistry
ISBN:
9781337398909
Author:
Lawrence S. Brown, Tom Holme
Publisher:
Cengage Learning
Chemistry & Chemical Reactivity
Chemistry
ISBN:
9781337399074
Author:
John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:
Cengage Learning
Chemistry & Chemical Reactivity
Chemistry
ISBN:
9781133949640
Author:
John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:
Cengage Learning
General Chemistry - Standalone book (MindTap Cour…
Chemistry
ISBN:
9781305580343
Author:
Steven D. Gammon, Ebbing, Darrell Ebbing, Steven D., Darrell; Gammon, Darrell Ebbing; Steven D. Gammon, Darrell D.; Gammon, Ebbing; Steven D. Gammon; Darrell
Publisher:
Cengage Learning