Michaelis-Menten kinetics are used to describe intracellular reactions. Yet [Eo] [So]. In in vitro batch reactors, the quasi-steady-state hypothesis does not hold for [Es] [So]. Similarly, the rapid equilibrium assumption also will not hold. Rationalize why Michaelis-Menten Kinetics and the quasi-steady-state approximation are still reasonable descriptions of intracellular enzyme reactions.

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter18: Chemical Kinetics
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Michaelis-Menten kinetics are used to describe intracellular reactions. Yet [Eo] [So]. In in vitro batch reactors, the quasi-steady-state hypothesis does not hold for [Es] [So]. Similarly, the rapid equilibrium assumption also will not hold. Rationalize why Michaelis-Menten Kinetics and the quasi-steady-state approximation are still reasonable descriptions of intracellular enzyme reactions.
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