Metformin is a commonly used treatment for type 2 diabetes. The active compound was isolated from the french lilac plant and was first used in the 1770s to treat individuals with excessive thirst and frequent urination (LaMoia & Shulman, 2020). Its exact mechanism of action is still under debate, but it ultimately works to lower blood glucose levels. Which of the following proposed mechanisms could explain how metformin works? O inhibits the function of liver glycogen synthase, an enzyme involved in glycogenesis O increases the release of glucagon by the pancreas O decreases gluconeogenesis in the liver O inhibits the breakdown of triglycerides in adipose tissue

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Metformin is a commonly used treatment for type 2 diabetes. The active compound was isolated
from the french lilac plant and was first used in the 1770s to treat individuals with excessive thirst
and frequent urination (LaMoia & Shulman, 2020). Its exact mechanism of action is still under
debate, but it ultimately works to lower blood glucose levels.
Which of the following proposed mechanisms could explain how metformin works?
O inhibits the function of liver glycogen synthase, an enzyme involved in glycogenesis
O increases the release of glucagon by the pancreas
O decreases gluconeogenesis in the liver
O inhibits the breakdown of triglycerides in adipose tissue
Transcribed Image Text:Metformin is a commonly used treatment for type 2 diabetes. The active compound was isolated from the french lilac plant and was first used in the 1770s to treat individuals with excessive thirst and frequent urination (LaMoia & Shulman, 2020). Its exact mechanism of action is still under debate, but it ultimately works to lower blood glucose levels. Which of the following proposed mechanisms could explain how metformin works? O inhibits the function of liver glycogen synthase, an enzyme involved in glycogenesis O increases the release of glucagon by the pancreas O decreases gluconeogenesis in the liver O inhibits the breakdown of triglycerides in adipose tissue
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