In the following diagram, A and B are two Okazaki fragments generated during DNA replication. Solid boxes represent the primers and dotted lines represent the newly synthesized DNA strands. A В Template DNA To which direction (towards the left or towards the right) is the replication fork is moving?

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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2. In the following diagram, A and B are two Okazaki fragments generated during DNA replication.
Solid boxes represent the primers and dotted lines represent the newly synthesized DNA strands.
A
В
Template DNA
To which direction (towards the left or towards the right) is the replication fork is moving?
a.
b. Which Okazaki fragment is synthesized first? Briefly explain why.
(i) Which enzyme in prokaryotes synthesizes the primers? On which strand (leading or lagging
strand) can we see primers?
с.
(ii) Give TWO similarities and TwO differences between the syntheses by the enzyme in (i)
and by the enzyme elongating a DNA strand?
(iii) Think about ONE possible consequence with a brief explanation if the primers were not
removed after DNA replication is completed.
Transcribed Image Text:2. In the following diagram, A and B are two Okazaki fragments generated during DNA replication. Solid boxes represent the primers and dotted lines represent the newly synthesized DNA strands. A В Template DNA To which direction (towards the left or towards the right) is the replication fork is moving? a. b. Which Okazaki fragment is synthesized first? Briefly explain why. (i) Which enzyme in prokaryotes synthesizes the primers? On which strand (leading or lagging strand) can we see primers? с. (ii) Give TWO similarities and TwO differences between the syntheses by the enzyme in (i) and by the enzyme elongating a DNA strand? (iii) Think about ONE possible consequence with a brief explanation if the primers were not removed after DNA replication is completed.
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