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- Locating Stereogenic Centers Locate the stereogenic centers in each drug. Albuterol is a bronchodilator— that is, it widens airways—so it is used to treat asthma. Chloramphenicol is an antibiotic used extensively in developing countries because of its low cost.Locate the stereogenic centers in each compound. A molecule may have one or more stereogenic centers. Gabapentin enacarbil [part (d)] is used to treat seizures and certain types of chronic pain.Saquinavir (trade name Invirase) belongs to a class of drugs called protease inhibitors, which are used to treat HIV (human immunodeficiency virus). OH CONH2 O saquinavir Trade name: Invirase NH a. Locate all stereogenic centers in saquinavir, and label each stereogenic center as R or S. b. Draw the enantiomer of saquinavir. c. Draw a diastereomer of saquinavir. d. Draw a constitutional isomer that contains at least one different functional group.
- Locate the stereogenic centers in each compound.What is the percent enantiomeric excess (ee) of a mixture that has 86% of one enantiomer and 14% of the other? 100% 43% 4% O 14% O 72% 614%Which of the following pairs of stereoisomers are related as enantiomers? a) A & B; C&D b) A& C; B&D c) A&D; B&C d) C&D; B&C
- If a mixture has an ee of 30%, what is the percentage enantiomer) of each enantiomer? (ee = excess Select one: OA. 85%: 15% 70% 30% B. O C. 75%: 25% O D. 65%: 35%H3C CH3 chiral achiral H H₂C CH3 H chiral achiral CI CH3 CH3 chiral achiral Br Br chiral achiralLocate the stereogenic centers in each drug. Albuterol is a bronchodilator—that is, it widens airways—so it is used to treat asthma. Chloramphenicol isan antibiotic used extensively in developing countries because of its lowcost.
- Captopril is a drug used to treat high blood pressure and congestiveheart failure.Designate each stereogenic center as R or S.Convert each three-dimensional representation into a Fischer projection.Which of the following represents enantiomers? CH2OH CH3 CH3 HI он HO ICH3 HO HI IOH HI HI ICH3 HO ICH3 H3C H CH3 OH он I II III IV А. I and II B. II and III C. III and IV D. II and III II