If 1ªCO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation.. SHOW MORE V Oxaloacetate b Citric acid Isocitric acid d a-Ketoglutarate e Succinyl-CoA f Succinate Fumarate Malate

If 1ªCO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation.. SHOW MORE V Oxaloacetate b Citric acid Isocitric acid d a-Ketoglutarate e Succinyl-CoA f Succinate Fumarate Malate

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter22: Medications Used For Gastrointestinal System Disorders

Section: Chapter Questions

Problem 10RQ

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If 1"co2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V a Oxaloacetate Citric acid Isocitric acid d a-Ketoglutarate e Succinyl-CoA Succinate Fumarate Malate b0
Question 11 Which carbons of glucose will be incorporated into Palmitic acid by the Fatty acid Synthase? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V a Carbon 1 Carbon 2 Carbon 3 d Carbon 4 e Carbon 5 f Carbon 6 All carbons will be incorporated. h No carbons will be incorporated.
Question 1. Put away your notes and text and draw the complete Calvin-Benson cycle starting from 3molecules of Ru1,5BP. Show stoichiometry along the way using 6 GAP molecules to regeneratethe 3 Ru1,5BPs. Label each reaction according to its enzyme class (your choices arecarboxylase, kinase, dehydrogenase, aldolase, epimerase, isomerase, phosphatase, andtransketolase – see the posted enzyme guide for help on this).
Question 1 Which of the following statements is true regarding compounds of the TCA cycle resulting from introduction into the TCA cycle of Glutamate labeled in the R group carboxyl carbon transaminated to a-Ketoglutarate and taken through one complete round back to Succinyl CoA? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V a After one complete round Succinyl CoA will be radioactive. b The labeled R group carboxyl of Glutamate will be released as radioactive carbon dioxide. The transfer of Acetyl-CoA to Oxaloacetate will be result in radioactive Citric Acid. d A possible source of radioactive carbon dioxide is the Isocitrate Dehydrogenase reaction. e A possible source of radioactive carbon dioxide is the a-Ketoglutarate Dehydrogenase reaction. f No released carbon dioxide is radioactive. If taken through two complete rounds Succinyl CoA produced will be radioactive. h The carbon of the…
Provide what is being asked for. Show all relevant calculations and summarize your answers in the table below. Summarize your final answers in the given table and append your complete solutions in the following page. Write zero (0) in the box if it is your answer. For each fatty acid given, determine the following. a. Gross ATP from ß-oxidation cycles b. Gross ATP from acetyl CoA produced C. Gross ATP from conversion of propionyl CoA (if applicable) d. Total number of ATP deducted e. Total net ATP A. FATTY ACIDS b C d i. 24:14 cis-9 fatty acid in the mitochondrion ii. 17:0 fatty acid in a mammalian cell where propionyl CoA is completely oxidized iii. fatty acids from the hydrolysis of the given TAG in a liver cell where amino acid and nucleotide biosynthesis is very active. a
QUESTION 34 Which of the following represents a reaction that could be used to refil the TCA cycle Aspartate -a -ketoglutarate Pyruvate Oxaloacetate O Oxaloacetate- Phosphoenol pyruvate Citrate - Oxaloacetate + acetyl COA
Question 4 If 32p – labeled (radioactive phosphate) inorganic phosphate were introduced to erythrocytes undergoing glycolysis which of the following molecules would you expect to detect 32 p in Glycolytic intermediates? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a Fructose 1-6 bisphosphate b 3-Phosphoglyceraldehyde Dihydroxyacetone phosphate d 2-Phosphoglycerate e 1-3 bisphosphoglycerate f Phosphoenolpyruvate 3-Phosphoglycerate h Pyruvate i None of the above
Provide what is being asked for. Show all relevant calculations and summarize your answers in the table below. Summarize your final answers in the given table and append your complete solutions in the following page. Write zero (0) in the box if it is your answer. For each fatty acid given, determine the following. a. Gross ATP from ß-oxidation cycles b. Gross ATP from acetyl CoA produced C. Gross ATP from conversion of propionyl CoA (if applicable) d. Total number of ATP deducted e. Total net ATP B. LACTOSE a b с d i. a liver cell with non-functional malate-aspartate shuttle* ii. a skeletal muscle cell lacking oxygen *Assume that the deficiency is isolated and will not influence the function of other respiration components
QUESTION 2 Consider the chemical transformation in the reaction shown below. Select the fermentation or gluconeogenesis enzyme that catalyzes the most similar type of transformation. NAD H NAD O: HO Pyruvate decarboxylase Lactate dehydrogenase/alcohol dehydrogenase O Pyruvate carboxylase O Phosphoenolpyruvate carboxykinase (PEPCK) Fructose 1,6-bisphosphatase/glucose 6-phosphatase
Question 3. Dihydrofolate reductase (DHFR) is capable of making one carbon moieties of various oxidation states (i.e., methanol, formaldehyde, formate). Folic acid, a B vitamin, provides the critical chemistry: R. This type of chemistry is utilized in the synthesis of nucleotides. Methotrexate has a significantly higher affinity (Kd - 50 pM) than folate for the enzyme and is used in cancer therapy to suppress DNA synthesis of rapidly dividing cancer cells. What is a tempting reason for methotrexate having such high affinity?
Which of the following statements are True? Multiple answers: Multiple answers are accepted for this question Select one or more answers and submit. For keyboard navigation. SHOW MORE V If [1-14C) Ribose-S-phosphate is incubated with a mixture of purified transketolase- transaldolase-phosphopentose isomerase-phosphopentose epimerase and glyceraldehyde-3-phosphate Fructose-6-phosphate will be labeled in the 1 and 3 positions. a Starting with Glucose 6-phosphate labelled in carbon number 1 with radioactive carbon and taken through the axidative phase of the Pentose Phosphate Pathway and the first transaldolase reaction gives rise to a 7-carbon intermediate labeled with radioactive carbon in carbon number 1. Avidin is a protein that binds extremely tight to biotin. So avidin would be a potent inhibitor of Acetyl CoA Carboxylase. The two electrons derived from the a-Ketoglutarate Dehydrogenase complex come from dihydrolipoic acid. In Fatty Acid synthesis carbon atoms 15 and 16 of Palmitic…
Question 2. An enzyme was found to convert Acetyl-coA to an acetyl-cysteine intermediate of the enzyme. The structure of cOA is: H H НО СН; HS — СH2— СH2 — N—C—CH,— CH2—N- С—С—С—CH;—0—Р- 0–CH2 Adenine н CH H H H Phosphopantetheine group of coenzyme A 2-O3PO ОН Draw a plausible chemical mechanism. Where is the acetyl-group in acetyl-coA? What is the reactive group of the protein? The reaction is enhanced at higher pH. How is this consistent with your mechanism? Is covalent catalysis involved?