How does the results of the bone marrow biopsy and the complete cell count (including HGB, HCT and MCV) justify this diagnosis

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter8: Blood
Section: Chapter Questions
Problem 1CT: Thrombocytopenia (throm-bo-sye-tow-pee-ne-ah) is a disorder that develops when certain drugs, bone...
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Look at the attached image. This is a male, age 51, who has hairy cell leukaemia. How does the results of the bone marrow biopsy and the complete cell count (including HGB, HCT and MCV) justify this diagnosis?
Story:
51 year old male, general health reported as OK, good diet perhaps a little loss of
appetite, regular exercise a little fatigued usually explained by over doing it at the gym'.
Patient was seen by his GP for a routine preoperative check before dental surgery. He was
found to have low haemoglobin and large left upper quadrant mass.
Complete blood count (CBC):
3.36 x 102/L
9.3 x 10/L
5.9 x 10/L
RBC
WBC
PLT
HGB
10.9
g/dL
HCT
31.2
MCV
92.8
fL
Neutrophils
Lymphocytes
14%
15%
Abnormal cells
71% (shown)
Bone marrow biopsy:
Aspirate: A small amount of fluid was aspirated, and showed 78.1% abnormal cells similar to
those in the blood smear.
Sections: Hypocellular with a diffuse loosely structured infiltrate of mononuclear cells.
Increased areas of fibrosis.
Cytochemistry: Tartrate resistant acid phosphatase (TRAP) stain of abnormal cells: positive
Transcribed Image Text:Story: 51 year old male, general health reported as OK, good diet perhaps a little loss of appetite, regular exercise a little fatigued usually explained by over doing it at the gym'. Patient was seen by his GP for a routine preoperative check before dental surgery. He was found to have low haemoglobin and large left upper quadrant mass. Complete blood count (CBC): 3.36 x 102/L 9.3 x 10/L 5.9 x 10/L RBC WBC PLT HGB 10.9 g/dL HCT 31.2 MCV 92.8 fL Neutrophils Lymphocytes 14% 15% Abnormal cells 71% (shown) Bone marrow biopsy: Aspirate: A small amount of fluid was aspirated, and showed 78.1% abnormal cells similar to those in the blood smear. Sections: Hypocellular with a diffuse loosely structured infiltrate of mononuclear cells. Increased areas of fibrosis. Cytochemistry: Tartrate resistant acid phosphatase (TRAP) stain of abnormal cells: positive
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