Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Genotype Number M1M1 20 M1M2 45 M2M2 42 M1M3 4 M2M3 8 M3M3 6 Total 125 a. Calculate the genotypic and allelic frequencies for this population. b. What would the expected numbers of genotypes be if the population were in Hardy–Weinberg equilibrium?

Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Genotype Number M1M1 20 M1M2 45 M2M2 42 M1M3 4 M2M3 8 M3M3 6 Total 125 a. Calculate the genotypic and allelic frequencies for this population. b. What would the expected numbers of genotypes be if the population were in Hardy–Weinberg equilibrium?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Calculate the genotypic and allelic frequencies for the population (round to the nearest thousandth). f(M1M1) = f(M1M2) = f(M2M2) = f(M1M3) = f(M2M3) = f(M3M3) = f(M1) = f(M2) = f(M3) = What would be the expected number of each genotype (round to the nearest whole number assuming genotype represents an individual) assuming the population was in Hardy Weinberg equilibrium? f(M1M1) = f(M1M2) = f(M2M2) = f(M1M3) = f(M2M3) = f(M3M3) = Referencing a p-value of 0.05 and a CV of 11.070, state if the population is in HWE. Genotype Observed Expected O–E (O–E)2 (O–E)2/E M1M1 M1M2 M2M2 M1M3 M2M3 M3M3 Chi-squared = Statement:…
You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype states, and observed the frequencies reported in the table below. a. Calculate D for genes A and B. (D = gAB9ab - gAb9aB) b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B? Frequency Allele A 0.6 Allele a 0.4 Allele B 0.8 Allele b 0.2 Haplotype AB Haplotype Ab Haplotype aB Haplotype ab 0.48 0.12 0.32 0.08
What is the first variable that can be calculated given these data, and what is the final variable we are requesting you to calculate? "In Finland, 256 people out of 10,000 are homozygous for the CCR5 allele mutation resulting in HIV resistance. Assuming the locus is in Hardy-Weinberg equilibrium, what is the expected genotype frequency of heterozygous carriers for the CCR5 mutation?"
Tay-Sachs disease in humans is caused by a recessive allele. The disease is characterized by mental deficiency and blindness, with death occurring by 4 years of age. Among Ashkenazi Jews of central European ancestry, about 1 in 3600 children is born with the disease. Assume Hardy-Weinberg equilibrium and calculate the frequency of the Tay- Sachs allele in this population. Round your answer to the nearest 0.001. Type your answer...
Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?
A total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1
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Identify each of the following as an example of allele, genotype,and/or phenotype frequency:A. Approximately 1 in 2500 individuals of Northern Europeandescent is born with cystic fibrosis.B. The percentage of carriers of the sickle cell allele in WestAfrica is approximately 13%.C. The number of new mutations per generation resultingin achondroplasia, a genetic disorder, is approximately5 × 10−5.
A study on blood types in a population found the following genotypic distribution among the people sampled: 1101 were MM, 1496 were MN and 503 were NN. i) calculate the allelic genotypic frequencies. ii) using x² test, determine whether or not this population is in Hardy-Weinberg equilibrium. Important information from the x² distribution is given in the picture attached.
The gamma globulin of human blood serum exists in two forms, Gm(a+) and Gm(a-), specified respectively by an autosomal dominant gene Gm(a+) and its recessive allele Gm(a-). Broman et al. (1963) recorded the tabulated phenotypic frequencies in three Swedish populations. Assuming the populations were at Hardy-Weinberg equilibrium, calculate the frequency of heterozygotes in each population.
(1 point) Humans with the genotypes DD and Dd show the Rh+ blood phenotype, whereas those with the genotype dd show the Rh- blood phenotype. In a sample of 400 Basques from Spain, 230 people were Rh+ and 170 people were Rh-. Assuming that this population is in Hardy-Weinberg proportions, what is the allele frequency of the allele D? (a) (a) 0.348 (answer) (b) (b) 0.652 (c) (c) 0.425 (d) (d) 0.575 (e) (e) 0.288 2. (2 points) In the Basque population mentioned above, what proportion of the Rh+ individuals would be expected to be heterozygote? (a) (a) 0.454 (b) (b) 0.789 (answer) (c) (c) 0.516 (d) (d) 0.250 (e) (e) 0.500 How is the answer for #2, b? please explain
Using the product rule, what is the total frequency of the profile, given the following genotype frequencies for each of the loci: D3S1358 = 0.04453 vWA = 0.02725 D5S818 = 0.07534 0.008406 0.0000914 0.14712 10,491 0.914208