Figure 1 shows the action potential graph recorded from a rat neurone and the potential changes obtained from the rat neurone when the concentration of potassium ([K*]out) and calcium ([Ca²+]out) are varied extracellularly in the bathing solution. (i) In the resting state, is the neuronal permeability to potassium more than, less than or equal to that of the permeability to calcium? Explain your answer. (ii) Vm 'The calcium ion concentrations are lower inside the cell than outside.' Justify this statement based on the graphs and the Nernst equation assuming the temperature is at 25 °C. Vm 30 0 -30 30 0 -30- 50 AP overshoot [K+ lout 100 150 time (msec) 30 RP Figure 1 0 -30 AP overshoot RP 200 250 AP overshoot [Ca²+ lout RP
Figure 1 shows the action potential graph recorded from a rat neurone and the potential changes obtained from the rat neurone when the concentration of potassium ([K*]out) and calcium ([Ca²+]out) are varied extracellularly in the bathing solution. (i) In the resting state, is the neuronal permeability to potassium more than, less than or equal to that of the permeability to calcium? Explain your answer. (ii) Vm 'The calcium ion concentrations are lower inside the cell than outside.' Justify this statement based on the graphs and the Nernst equation assuming the temperature is at 25 °C. Vm 30 0 -30 30 0 -30- 50 AP overshoot [K+ lout 100 150 time (msec) 30 RP Figure 1 0 -30 AP overshoot RP 200 250 AP overshoot [Ca²+ lout RP
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 1RE: Conformational changes in channel proteins brought about by voltage changes are responsible for...
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