Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
f) As ATP is used, the above, at what ratio of equilibrium)? phosphocreatine stores are depleted. Using the ATP and ADP concentrations given [creatine]/[phosphocreatine] would you expect the reaction to stop (or reach G) do some research. How does the level of phosphocreatine remain high in muscle cells. Where/how is it remade from creatine? (one paragraph)

f) As ATP is used, the above, at what ratio of equilibrium)? phosphocreatine stores are depleted. Using the ATP and ADP concentrations given [creatine]/[phosphocreatine] would you expect the reaction to stop (or reach G) do some research. How does the level of phosphocreatine remain high in muscle cells. Where/how is it remade from creatine? (one paragraph)

Biochemistry
Biochemistry
9th Edition
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Chapter6: The Behavior Of Proteins: Enzymes
Section: Chapter Questions
Problem 60RE
See similar textbooks
icon
Related questions
Question

f and g 

asap 

Energy Conversion Problem - 2022 1. a) Influence of concentration on the free energy change. In frog muscle, the concentrations of ATP, ADP, and phosphate are 1.25x10-³ M, 0.50x10-³ M, and 2.50 x10-³ M respectively. Write the reaction and the reaction quotient, Q. Calculate the free energy change, AG', for the hydrolysis of ATP in muscle cells. Assume that AG"=-31.0 kJ mol-¹ for the hydrolysis of ATP, the temperature is 25°C, and the pH=7. Q=(0.50x10-³ M)(1.25x10-³ M)/(2.50 x10-³ M) = 1.25 x 10-6 M/1.25 x 10-³ M = 1 x 10-³ M A Gº'= -31.0 kJ/mol + (8.314 kJ /mol K_) (298 K) ( [0.5 × 10-³] [2.5 × 10-³] / [1.25 × 10-³])= −48.1 kJ/mol b) For this system, what is the maximum amount of work that can be done per mole of ATP hydrolyzed? W max, by the system =-W max, on the surroundings = -ArG' = 48.1 kJ/mol c) In muscle, phosphocreatine serves as a carrier of chemical energy. It can transfer its phosphate group to ADP to replenish the ATP used in muscle contraction. This is an example of energy coupling- using the energy of a very favorable reaction to drive an unfavorable reaction. The enzyme creatine phosphokinase catalyzes the reaction: Net rxn creatine phosphokinase phosphocreatine + ADP d) Show above how you calculate AGº' for the net reaction given that the hydrolysis for phosphocreatine is AG0¹ -43.1 kJ mol-¹. e) Calculate the equilibrium constant of this reaction. phosphocreatine + H2O → creatine + Pi Pi + ADP → ATP + H2O = -43.1 kJ mol = 31.0 kJ mol creatine + ATP bosphocreatine + ADP → creatine + ATP = -12.1 kJ mol K-e 12.1 kj/mol / (8.314 x 10-³ kj/mol k) (298K) K-e 4.89 K= 132.4 AG⁰¹ ???? kJ mol-1 f) As ATP is used, the phosphocreatine stores are depleted. Using the ATP and ADP concentrations given above, at what ratio of [creatine]/[phosphocreatine] would you expect the reaction to stop (or reach equilibrium)? G) do some research. How does the level of phosphocreatine remain high in muscle cells. Where/how is it remade from creatine? (one paragraph)
Transcribed Image Text:Energy Conversion Problem - 2022 1. a) Influence of concentration on the free energy change. In frog muscle, the concentrations of ATP, ADP, and phosphate are 1.25x10-³ M, 0.50x10-³ M, and 2.50 x10-³ M respectively. Write the reaction and the reaction quotient, Q. Calculate the free energy change, AG', for the hydrolysis of ATP in muscle cells. Assume that AG"=-31.0 kJ mol-¹ for the hydrolysis of ATP, the temperature is 25°C, and the pH=7. Q=(0.50x10-³ M)(1.25x10-³ M)/(2.50 x10-³ M) = 1.25 x 10-6 M/1.25 x 10-³ M = 1 x 10-³ M A Gº'= -31.0 kJ/mol + (8.314 kJ /mol K_) (298 K) ( [0.5 × 10-³] [2.5 × 10-³] / [1.25 × 10-³])= −48.1 kJ/mol b) For this system, what is the maximum amount of work that can be done per mole of ATP hydrolyzed? W max, by the system =-W max, on the surroundings = -ArG' = 48.1 kJ/mol c) In muscle, phosphocreatine serves as a carrier of chemical energy. It can transfer its phosphate group to ADP to replenish the ATP used in muscle contraction. This is an example of energy coupling- using the energy of a very favorable reaction to drive an unfavorable reaction. The enzyme creatine phosphokinase catalyzes the reaction: Net rxn creatine phosphokinase phosphocreatine + ADP d) Show above how you calculate AGº' for the net reaction given that the hydrolysis for phosphocreatine is AG0¹ -43.1 kJ mol-¹. e) Calculate the equilibrium constant of this reaction. phosphocreatine + H2O → creatine + Pi Pi + ADP → ATP + H2O = -43.1 kJ mol = 31.0 kJ mol creatine + ATP bosphocreatine + ADP → creatine + ATP = -12.1 kJ mol K-e 12.1 kj/mol / (8.314 x 10-³ kj/mol k) (298K) K-e 4.89 K= 132.4 AG⁰¹ ???? kJ mol-1 f) As ATP is used, the phosphocreatine stores are depleted. Using the ATP and ADP concentrations given above, at what ratio of [creatine]/[phosphocreatine] would you expect the reaction to stop (or reach equilibrium)? G) do some research. How does the level of phosphocreatine remain high in muscle cells. Where/how is it remade from creatine? (one paragraph)
Expert Solution
steps

Step by step

Solved in 2 steps with 2 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
SEE MORE TEXTBOOKS