please please help me to answer it >>> i have an exam
Human xanthine oxidase catalyzes the oxidation of hypoxanthine to xanthine and can further
catalyze the oxidation of xanthine to uric acid. For the treatment of hyperuricemia and gout,
several medications are used to inhibit the activity of xanthine oxidase and reduce the
production of uric acid. You are a biochemist and just discovered a chemical that can inhibit
the activity of the human xanthine oxidase. When analyzing its mode of inhibition, you found
that the enzyme inhibitor complex requires 450 J.mol
-1 to dissociate and that it displays
kinetics somehow similar to noncompetitive inhibition. You sent your inhibitor to the ministry
of health for approval as a medication for gout. Based on the data provided, are they going to
authorize it as a medication or not? Explain?
Human xanthine oxidase is an enzyme that catalyses the oxidation of hypoxanthine to xanthine and further catalyses the oxidation of xanthine to uric acid. It is the enzyme responsible for hyperuricemia and gout.
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