Renal DiseaseSuppose ten patients with advanced diabetic nephropathy (kidney complications of diabetes) were treatedwith captopril over an 8-week period. Urinary protein was measured before and after drug therapy, withresults listed in the table below in both the raw and In scale. (Let population 1 be the measurement aftertreatment and population 2 be the measurement before treatment. Use after - before.)Changes in urinary protein after treatment with captoprilPatient12345678910Raw scale urinary protein(g/24 hr)BeforeUSE SALT25.717.115.910.58.17.85.75.55.04.8After10.25.65.73.56.40.86.24.62.12.8In scale urinary protein(g/24 hr)Before3.24652.83912.76632.35142.09192.05411.74051.70471.60941.5686After2.32241.72281.74051.25281.8563-0.22311.82451.52610.74191.0296(a) What is the appropriate statistical procedure to test whether mean urinary protein has changed overthe 8-week period? (You may need to use the Distribution Calculators page in SALT to checkconditions.) Pq 3 All answers are correct.Please explain clearly how to solve (c) *Find the test statistic. (Round your answer to two decimal places.)and (d)kThanks !!3.88Use technology to find the p-value. (Round your answer to four decimal places.)p-value = 0.0037State your conclusion.Reject Ho. There is insufficient evidence to conclude that there is a significant change in meanIn(urinary protein) over the 8-week period.Fail to reject Ho. There is insufficient evidence to conclude that there is a significant change inmean In(urinary protein) over the 8-week period.%O Fail to reject Ho. There is sufficient evidence to conclude that there is a significant change inmean In(urinary protein) over the 8-week period.Reject Ho. There is sufficient evidence to conclude that there is a significant change in meanIn(urinary protein) over the 8-week period.Are there any advantages to using the raw or the In scale?beSince the difference scores appear to ---Select--- related to the initial urinary protein, the---Selectcale-scale is preferable here.(c) What is your best estimate of the percent change in urinary protein based on the data in the table?(Round your answer to two decimal places.)%(d) Provide a 95% CI (in percent) associated with your estimate in part (c). (Enter your answer usinginterval notation. Round your numerical values to two decimal places.)Need Help? Read It

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Consider X1 and X2 be the two random variables representing the measurements (in scale) after and…