Briefly describe the events leading to the synthesis of viral proteins. Begin with the genome; assume this is a negative single-stranded RNA virus (-SSRNA).
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- Answer in complete sentences and paragraphs. Draw the diagram by hand and make a table to compare and contrast: Diagram the viral replication cycle for both an enveloped DNA and nonenveloped RNA virus. Compare and contrast lytic and budding release mechanisms. Relate the release mechanisms to lytic and chronic infections.What is the mode of replication of the virus? (This can be presented as a diagram with narrative description)List three differences between the structure of HIV and the virus that causes influenza. For one of these differences, explain how the STRUCTURE is key to the FUNCTION of the virus.
- Answer the following regarding the varicella-zoster virus: a) the biology of the virus ( type: DNA/RNA type: single or double stranded) b) how it replicates c) life cycle of the virus (binding, fusion, reverse transcription, integration, replication, and assembly)Indicate whether the following sentences is either True or False and CORRECT the wrong sentences ( please answer the two questions 1 and 2) : 1. Simian Virus 40 (SV40) is an example of is a circular ssDNA belong to Polyomavirus, was first isolated from primary cell cultures derived from rhesus monkey kidneys, and activates p53. 2. SARS-COV-2 is an enveloped, icosahedral virus that is surrounded by a lipid bilayer and causes COVID-19 pandemic .Answer the following and inlcude the references SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? Do you think that ART combinations/options might help in suppressing the viral replication of SARS-CoV-2? Expound.
- The herpes virus is a very large family of viruses which can cause human infections. There are many varioustypes which can cause different types of effects. Please discuss how you would determine which type of virus is causing the infection. Make sure to include 2-3 examples and how this will help differentiate between each.Please provide a general definition of a virus. Viruses can cause other issues, known as cytopathic effects. Provide 3 effects and discuss why that effect can be very damaging to the host.Describe the etiology/aetiology, morphology, and pathogenesis of the Zika virus. Note: You have to use the knowledge of “Clinical biochemistry” as a foundation for your answers. Please explain in details
- Explain the mechanism by which some (+)ssRNA viruses are able to produce many (e.g. ~10) proteins from a single RNA.Explain gene editing to correct genetic defects in humans using an adenovirus.Match each of the following replication classes of viruses with the one description that best describes it. This virus class is composed of segmented and non-segmented helical viruses that carry an RdRp within the virion into the cell. Example: Rabies virus These viruses are non- enveloped, icosahedral, have segmented genomes, and carry their own RNA-dependent RNA polymerase. The viral genome is copied following assembly. Example: Reovirus This is the only class of RNA viruses whose genome is replicated by cellular enzymes and not an RNA-dependent RNA polymerase. Cellular DNA polymerases replicate this virus's non- integrated genome, although transcription is not the initial event that takes place in the process. Example: Parvoviruses In this class of viruses, transcription occurs before genome replication because viral proteins are involved in replicating the genome. Example: Adenovirus This class of viruses forms circular DNA and creates pre- genomic RNA using host RNA polymerases.…