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- uizzes/67365/take Based on the image below, select the correct statements. Note: There may be more than 1 correct response. I Ribose 5-phosphate ribose phosphate pyrophosphokinase (PRPP synthetase) glutamine-PRPP amidotransferase adenylosuccinate synthetase AMP > 5-Phosphoribosylamine I adenylosuccinate PRPP lyase 9 steps Adenylosuccinate AMP IMP <-- ADP - AMP <-- GMP <-- IMP IMP dehydrogenase <- GMP - XMP ADP ATP GMP يمد XMP-glutamine amidotransferase Increased levels of ADP inhibit the production of PRPP. Increased levels of GMP inhibit the production of XMP. O Increased ADP activates PRPP synthase to increase PRPP levels. Increased IMP activates glutamine-PRPP amidotransferase to further increase IMP levels. 8 OBCBased on the image below, select the correct statements. Note: There may be more than 1 correct response. Ribose 5-phosphate ribose phosphate pyrophosphokinase (PRPP synthetase) glutamine-PRPP amidotransferase adenylosuccinate synthetase AMP -> PRPP 5-Phosphoribosylamine I adenylosuccinate lyase 9 steps Adenylosuccinate AMP IMP <-- ADP <- AMP <-- GMP <-- IMP IMP dehydrogenase <- GMP. XMP ADP ATP XMP-glutamine amidotransferase GMP يا Increased levels of ADP inhibit the production of PRPP. Increased levels of GMP inhibit the production of XMP. Increased ADP activates PRPP synthase to increase PRPP levels. Increased IMP activates glutamine-PRPP amidotransferase to further increase IMP levels.In some organisms, isoleucine can be synthesized in a multi-step procedure (a series of enzymatic reactions), beginning with a molecule of threonine. Keeping that in mind explain the experimental results below. Amount of endproduct Activity of threonine (isoleucine) deaminase None Low Medium High Very high High Moderate Very low
- the following is a coenzyme or cofactor involved in enzymatic reaction. identify the biochemical role that S-adenosylmethionine plays within a biochemical tranformation.Based on the image below, select the correct statement HN Aspartate Rib-P Inosinate (IMP) IMP H₂O OOC-CH₂- COO NH Fumarate N 274 adenylosuccinate lyase Rib-P Adenylosuccinate GTP GDP + P₁ adenylosuccinate IMP synthetase NAD+ NADH + H+ dehydrogenase Figure 22-36 Lehninger Principles of Biochemistry, Sixth Edition ©2013 W. H. Freeman and Company H HN H -N Gin Rib P Xanthylate (XMP) NH₂ Rib P Adenylate (AMP) Glu ATP AMP + PP₁ XMP-glutamine amidotransferase HN H₂N O GTP is phosphorylated in the conversion of IMP to GMP GTP is phosphorylated in the convertion of IMP to AMP GTP is dephosphorylated in the conversion of IMP to GMP O GTP is dephosphorylated in the conversion of IMP to AMP Rib-P Guanylate (GMP) GMPTetrodotoxin identify the species which releases the toxin (if it is man-made then this will be all that is required for this part) identify the step disrupted in the neuromuscular junction pathway Provide any consequences of this disruption. Does the toxin have any applications in biomedicine as a painkiller, disease treatment or analgesic? Provide your source in APA format for each. If this is missing no credit will be awarded.
- pluginfile.php/7382296/mod_resource/content/0/Purine%20Practice%20Pathway.pdf 1 / 1 67% Purine * Know regulatory steps Synthesis *Know how GTP and ATP control production O D-O O-0 R-5 P 5-phosphoribas ylamine EZ 9 oteps IMP ロロ AMP GMP E3 ES E7 LADP E4 Eb ATP JATP GTP typRefer to the figure. Portions of three biosynthetic pathways regulated through feedback inhibition and activation are shown. Two of these pathways intersect at carbamoyl phosphate. The third pathway generates a product that activates production of carbamoyl phosphate through allosteric modification of the enzyme carbamoyl phosphate synthetase. Arginine pathway Pyrimidine pathway Glutamate СТР Purine pathway N-acetylglutamate synthetase N-acetylglutamate UMP UMP ATCase Ornithine СР CO, + ATP Carbamoyl phosphate synthetase + Gin t-Arginine In this set of pathways, arginine biosynthesis is shut down through feedback inhibition when and arginine reach high levels of concentration. О СТР O ornithine O UMP O carbamoyl phosphate O glutamateBotulinum Toxin identify the species which releases the toxin (if it is man-made then this will be all that is required for this part) identify the step disrupted in the neuromuscular junction pathway Provide any consequences of this disruption. Does the toxin have any applications in biomedicine as a painkiller, disease treatment or analgesic? Provide your source in APA format for each. If this is missing no credit will be awarded.
- Trelstar® is an injectable formulation of polylactide-co-glycolide (PLGA) microspheresencapsulating triptorelin palmoate (Mw 13115 Da), a synthetic decapeptide agonist analog ofgonadotropin releasing hormone (GnRH). The medicine is used in treatment of patients withprostate cancer. The pharmacokinetics of triptorelin palmoate as free drug follows a 3 compartmentmodel with drug half-lives estimated to be 6 minutes, 45 minutes, and 3 hours, respectively. Threedifferent dosing intervals of Trelstar® are available in clinic: 1 month (3.75 mg), 3 month (11.25mg) and 6 month (containing 22.5 mg of drug).Discuss how encapsulation into PLGA microspheres improves patient therapy with triptorelinpalmoate, and how three dosing intervals available in clinic may have been achieved bymodifications in the formulationWhat step ends the first-half of the chymotrypsin mechanism? Attack of water on the acyl-enzyme intermediate. Selected Collapse of the first tetrahedral intermediate, releasing of the C-terminal peptide fragment and formation of the acyl-enzyme intermediate. Deprotonation of serine by the histidine. Collapse of the second tetrahedral intermediate leading to the final products. REVIEW QUESTION 1/1 CONTINUE MacBook Pro https://virginiacommonwealth.instructure.com/courses/42082/assignments/271397 esc OTWrite schematically the synthesis of phosphatidylcholine from phosphatidylethanolamine. What compounds are necessary for this biochemical process? Biological significance of phospholipids.