In a study, cats were fasted overnight, then given a single meal complete in all amino acids except arginine. Within two hours, blood ammonia levels increased from a normal level of 18 µg/L to 140 µg/L, and the cats showed the clinical symptoms of ammonia toxicity. A control group fed a complete amino acid diet, or an amino acid diet in which ornithine replaced arginine, showed no unusual clinical symptoms. What was the role of fasting in the experiment? to lower blood glucose levels O to help diagnose arginase deficiency disease to reduce benzoate and phenylbutyrate in the blood to elevate blood creatine kinase levels Why did the absence of arginine lead to ammonia toxicity? O Arginine allosterically activates carbamoyl phosphate synthetase I. Arginine facilitates the metabolism of NH in the urea cycle. Arginine facilitates the metabolism of NH+ in the What caused the ammonia levels to rise in the experimental group? oxidative deamination of glutamate O increased glycolytic activity O increased gluconeogenic activity O enzymatic degradation of a-ketoglutarate Is arginine an essential amino acid in cats? Why or why not? Arginine is not an essential amino acid because ornithine in the diet effectively replaces it. Arginine is an essential amino acid because its synthesis is not sufficient to meet the cats' needs. Arginine is an essential amino acid because Why did the absence of arginine lead to ammonia toxicity? O Arginine allosterically activates carbamoyl phosphate synthetase I. Arginine facilitates the metabolism of NH in the urea cycle. Arginine facilitates the metabolism of NH in the citric acid cycle. Arginine transports NH3 to the liver. Why can ornithine substitute for arginine? Ornithine is the immediate precursor to arginine. Ornithine is a synthetic version of arginine. The citric acid cycle converts ornithine to arginine. The urea cycle converts ornithine to arginine. Is arginine an essential amino acid in cats? Why or why not? O Arginine is not an essential amino acid because ornithine in the diet effectively replaces it. Arginine is an essential amino acid because its synthesis is not sufficient to meet the cats' needs. Arginine is an essential amino acid because overnight fasting depletes the blood's amino acid levels. Arginine is not an essential amino acid because ornithine has the same metabolic function as arginine.
In a study, cats were fasted overnight, then given a single meal complete in all amino acids except arginine. Within two hours, blood ammonia levels increased from a normal level of 18 µg/L to 140 µg/L, and the cats showed the clinical symptoms of ammonia toxicity. A control group fed a complete amino acid diet, or an amino acid diet in which ornithine replaced arginine, showed no unusual clinical symptoms. What was the role of fasting in the experiment? to lower blood glucose levels O to help diagnose arginase deficiency disease to reduce benzoate and phenylbutyrate in the blood to elevate blood creatine kinase levels Why did the absence of arginine lead to ammonia toxicity? O Arginine allosterically activates carbamoyl phosphate synthetase I. Arginine facilitates the metabolism of NH in the urea cycle. Arginine facilitates the metabolism of NH+ in the What caused the ammonia levels to rise in the experimental group? oxidative deamination of glutamate O increased glycolytic activity O increased gluconeogenic activity O enzymatic degradation of a-ketoglutarate Is arginine an essential amino acid in cats? Why or why not? Arginine is not an essential amino acid because ornithine in the diet effectively replaces it. Arginine is an essential amino acid because its synthesis is not sufficient to meet the cats' needs. Arginine is an essential amino acid because Why did the absence of arginine lead to ammonia toxicity? O Arginine allosterically activates carbamoyl phosphate synthetase I. Arginine facilitates the metabolism of NH in the urea cycle. Arginine facilitates the metabolism of NH in the citric acid cycle. Arginine transports NH3 to the liver. Why can ornithine substitute for arginine? Ornithine is the immediate precursor to arginine. Ornithine is a synthetic version of arginine. The citric acid cycle converts ornithine to arginine. The urea cycle converts ornithine to arginine. Is arginine an essential amino acid in cats? Why or why not? O Arginine is not an essential amino acid because ornithine in the diet effectively replaces it. Arginine is an essential amino acid because its synthesis is not sufficient to meet the cats' needs. Arginine is an essential amino acid because overnight fasting depletes the blood's amino acid levels. Arginine is not an essential amino acid because ornithine has the same metabolic function as arginine.
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Transcribed Image Text:In a study, cats were fasted overnight, then given a single meal complete in all amino acids except arginine. Within two hours,
blood ammonia levels increased from a normal level of 18 µg/L to 140 µg/L, and the cats showed the clinical symptoms of
ammonia toxicity. A control group fed a complete amino acid diet, or an amino acid diet in which ornithine replaced arginine,
showed no unusual clinical symptoms.
What was the role of fasting in the experiment?
to lower blood glucose levels
O to help diagnose arginase deficiency disease
to reduce benzoate and phenylbutyrate in the blood
to elevate blood creatine kinase levels
Why did the absence of arginine lead to
ammonia toxicity?
O Arginine allosterically activates carbamoyl
phosphate synthetase I.
Arginine facilitates the metabolism of NH in the
urea cycle.
Arginine facilitates the metabolism of NH+ in the
What caused the ammonia levels to rise in the
experimental group?
oxidative deamination of glutamate
O increased glycolytic activity
O increased gluconeogenic activity
O enzymatic degradation of a-ketoglutarate
Is arginine an essential amino acid in cats? Why or
why not?
Arginine is not an essential amino acid because
ornithine in the diet effectively replaces it.
Arginine is an essential amino acid because its
synthesis is not sufficient to meet the cats' needs.
Arginine is an essential amino acid because
Transcribed Image Text:Why did the absence of arginine lead to
ammonia toxicity?
O Arginine allosterically activates carbamoyl
phosphate synthetase I.
Arginine facilitates the metabolism of NH in the
urea cycle.
Arginine facilitates the metabolism of NH in the
citric acid cycle.
Arginine transports NH3 to the liver.
Why can ornithine substitute for arginine?
Ornithine is the immediate precursor to arginine.
Ornithine is a synthetic version of arginine.
The citric acid cycle converts ornithine to arginine.
The urea cycle converts ornithine to arginine.
Is arginine an essential amino acid in cats? Why or
why not?
O Arginine is not an essential amino acid because
ornithine in the diet effectively replaces it.
Arginine is an essential amino acid because its
synthesis is not sufficient to meet the cats' needs.
Arginine is an essential amino acid because
overnight fasting depletes the blood's amino
acid levels.
Arginine is not an essential amino acid because
ornithine has the same metabolic function
as arginine.
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