Homework Help is Here – Start Your Trial Now!
Science
Biology
Answers to choose from:   double stranded break repair              base excision repair              nucleotide excision repair              mismatch repair              light dependent DNA repair

Answers to choose from:   double stranded break repair              base excision repair              nucleotide excision repair              mismatch repair              light dependent DNA repair

Biochemistry
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 22P
See similar textbooks
icon
Related questions
Question

Answers to choose from:

 

double stranded break repair           

 

base excision repair           

 

nucleotide excision repair           

 

mismatch repair           

 

light dependent DNA repair      

Match the descriptions to the type of DNA Repair. A methylated cytosine is deaminated. This forms thymine, a normal base, except that it is across from guanine (the correct partner for cytosine). A protein recognizes the mis-pairing and recruits repair enzymes to cut out that section of the DNA strand and replace the strand via complementary base pairing. During replication, DNA pol III mistakenly adds an adenine across from a guanine. The proof-reading subunit of the polymerase recognizes the error, the polymerase backs up, uses its 3' to 5' exonuclease activity to cut out the last few bases that it laid down. Then it goes forward again making the new strand using the template. Glycosylase enzymes scan DNA for damages to individual nitrogenous bases in the DNA. If they find damaged bases, they cut that individual nitrogenous base out of the dsDNA, which is then replace by DNA Pol I. The covalent bonds forming the thymine-dimer are cleaved so that the DNA strand is normal again. No bases are removed or replaced. Choose] [Choose ] [Choose] [Choose ]
Transcribed Image Text:Match the descriptions to the type of DNA Repair. A methylated cytosine is deaminated. This forms thymine, a normal base, except that it is across from guanine (the correct partner for cytosine). A protein recognizes the mis-pairing and recruits repair enzymes to cut out that section of the DNA strand and replace the strand via complementary base pairing. During replication, DNA pol III mistakenly adds an adenine across from a guanine. The proof-reading subunit of the polymerase recognizes the error, the polymerase backs up, uses its 3' to 5' exonuclease activity to cut out the last few bases that it laid down. Then it goes forward again making the new strand using the template. Glycosylase enzymes scan DNA for damages to individual nitrogenous bases in the DNA. If they find damaged bases, they cut that individual nitrogenous base out of the dsDNA, which is then replace by DNA Pol I. The covalent bonds forming the thymine-dimer are cleaved so that the DNA strand is normal again. No bases are removed or replaced. Choose] [Choose ] [Choose] [Choose ]
Expert Solution
steps

Step by step

Solved in 3 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Tissue regeneration & repair
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
SEE MORE TEXTBOOKS