Analogs of hemidesmosomes are the focal contact sites, which are also sites where the cell attaches to the extracellular matrix. These junctions are prevalent in fibroblasts but largely absent in epithelial cells. on the other hand, hemidesmosomes are prevalent in epithelial cells but absent in fibroblasts. In focal contact sites, intracellular connections are made to actin filaments, whereas in hemidesmosomes connections are made to intermediate filaments. Why do you suppose these two different cell types attach differently to the extracellular matrix?

Analogs of hemidesmosomes are the focal contact sites, which are also sites where the cell attaches to the extracellular matrix. These junctions are prevalent in fibroblasts but largely absent in epithelial cells. on the other hand, hemidesmosomes are prevalent in epithelial cells but absent in fibroblasts. In focal contact sites, intracellular connections are made to actin filaments, whereas in hemidesmosomes connections are made to intermediate filaments. Why do you suppose these two different cell types attach differently to the extracellular matrix?

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter3: The Plasma Membrane And Membrane Potential

Section: Chapter Questions

Problem 7RE

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Tumors associated with breast cancer usually arise from either epithelial cells or fibroblasts. Because optimal treatment differs depending on the cellular origin of the tumor, it’s important for doctors to determine which cell type is present in a tumor. Unfortunately, the distinctive morphology of epithelial cells is lost when they become cancerous, so this determination cannot be made based on cell shape alone. How might determination of the class(es) of intermediate filaments present in tumor cells aid a doctor in figuring out which cell type is involved in the tumor?
If the graph represents one actin filament, and line A represents dynamic activity at the plus end and line B represents dynamic activity at the minus end, which of the following must be true? Group of answer choices Formin proteins have been removed. Treadmilling is occurring at 1000 mM. CapZ proteins are not present. Nucleation is occurring at 100 mM.
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Discuss about Intercellular and intracellular interactions ofclassical cadherins in typical adherens junctions.