Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CH₂OH

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter20: Acidity And Pka Of Phenols
Section: Chapter Questions
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Acyl transfer (nucleophilic substitution at carbonyl) reactions
proceed in two stages via a "tetrahedral intermediate." Draw
the tetrahedral intermediate as it is first formed in the
following reaction.
CH3OH
H3C
CI
•
•
•
•
You do not have to consider stereochemistry.
Include all valence lone pairs in your answer.
Do not include counter-ions, e.g., Na+, I", in your
answer.
In cases where there is more than one answer, just
draw one.
Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CH3OH H3C CI • • • • You do not have to consider stereochemistry. Include all valence lone pairs in your answer. Do not include counter-ions, e.g., Na+, I", in your answer. In cases where there is more than one answer, just draw one.
Acyl transfer (nucleophilic substitution at carbonyl) reactions
proceed in two stages via a "tetrahedral intermediate." Draw
the tetrahedral intermediate as it is first formed in the
following reaction.
H3C
CH3
H₂O
+ NaOH
• You do not have to consider stereochemistry.
Include all valence lone pairs in your answer.
•
• Do not include counter-ions, e.g., Na+, I, in your
answer.
Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H3C CH3 H₂O + NaOH • You do not have to consider stereochemistry. Include all valence lone pairs in your answer. • • Do not include counter-ions, e.g., Na+, I, in your answer.
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