5. The acyl group is a protecting group for amines which can be deprotected by treatment with sodium hydroxide. Please write mechanisms for both the protection and deprotection steps. NaOH 人人 CH30-H NH2 NH2 protect deprotect amine acetic anhydride N-acyl amine
5. The acyl group is a protecting group for amines which can be deprotected by treatment with sodium hydroxide. Please write mechanisms for both the protection and deprotection steps. NaOH 人人 CH30-H NH2 NH2 protect deprotect amine acetic anhydride N-acyl amine
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter19: Carboxylic Anhydrides, Esters, And Amides
Section: Chapter Questions
Problem 19.43P
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![5. The acyl group is a protecting group for amines which can be deprotected by
treatment with sodium hydroxide. Please write mechanisms for both the protection
and deprotection steps.
NaOH
CH30-H
NH2
protect
deprotect
R
NH2
amine
acetic anhydride
N-acyl amine](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe76ff820-0e16-44b9-9fb7-9d76f2e96cbb%2F6f845ec0-deec-406a-8bbc-167320116ef6%2Fyofz2qk_processed.jpeg&w=3840&q=75)
Transcribed Image Text:5. The acyl group is a protecting group for amines which can be deprotected by
treatment with sodium hydroxide. Please write mechanisms for both the protection
and deprotection steps.
NaOH
CH30-H
NH2
protect
deprotect
R
NH2
amine
acetic anhydride
N-acyl amine
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