2. Explain why the following Williamson ether synthesis will not work. 1) NaH 2) Br- OH X Propose an alternative synthesis for the desired target molecule by filling in the starting material and the reagent or molecule needed for step 2 in the reaction conditions in the boxes below. 1) NaH 2)

2. Explain why the following Williamson ether synthesis will not work. 1) NaH 2) Br- OH X Propose an alternative synthesis for the desired target molecule by filling in the starting material and the reagent or molecule needed for step 2 in the reaction conditions in the boxes below. 1) NaH 2)

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter16: Synthesis Workshop 1

Section: Chapter Questions

Problem 25E

See similar textbooks

Related questions

Q: For number 11: If 185 g of methanol are used up in a combustion process, what is the mass of H2O…

A: A balanced chemical equation contain equal number of atoms of each elements on both sides of the…

Q: Question: 1 .HA is a weak acid. Its ionization constant, Ka, is 1.3 x 10-13. Calculate the pH of an…

A: 1) To calculate the pH of an aqueous solution of a weak acid, you need to consider the ionization of…

Q: 4.003 82 207.2 83 209.0 84 (209) 85 Bi At Bismuth Astatine 2 He Pb Helium Lead An atom of…

A: As we know , During the radioactive decay , mass is conserved as it follows law of conservation of…

Q: Figure CH3 H₂C-C-CH₂OH H H₂C- CH₁ H NH₂ reagent H₂C reagent C CH3 H OH reagent B = note H₂C H 1 of 1…

A: Alcohols on oxidation with K2Cr2O7/ H2SO4 give carboxylic acids. Carboxylic acid on reaction with…

Q: Urea [(NH₂)2CO] is used for fertilizer and many other things. Calculate the number of N, C, O, and H…

A: Given,The formula of Urea = (NH2)2COmass of urea = 2.99 x 104 g

Q: For this sequence of reactions, draw the major organic product of step 4 .

A: It is based on the concept of reactivity of alkene Here we are required to find the major product…

Q: An atomic cation with a charge of +1 has the following electron configuration: [He] 2s²2p¹ What is…

A: Detail

Q: Rank the following solutions according to their acidity: Rank Solution 1 pH = 7 [H₂0+] = 10-10 M…

A: pH : pH can be defined as the negative logarithm of hydrogen ion concentration pH = -log[H+] pH +…

Q: In the energy diagram shown for the addition of HBr to 1,3-butadiene, A is the thermodynamic product…

A: In reaction, here in addition reaction, the product formation is takes place by two ways, Kinetic…

Q: For many purposes we can treat nitrogen (N₂) as an ideal gas at temperatures above its boiling point…

A: The relationship between the temperature, pressure, and volume of the initial and final state of an…

Q: Draw a second resonance structure for each species. a. CH3-C=C-C-CH3 II b. CH3-C-CH3 :CI: Η Η Η C.…

Q: This energy diagram shows the allowed energy levels of an electrpn in a certain atom. (Note: the SI…

Q: Three bottles are labelled as shown: Bottle 1 0.001 mol/L HCl(aq) Bottle 2 0.003 mol/L HBr(aq)…

Q: What is the electrostatic potential energy (in joules) between an electron and a proton that are…

A: The capacity of a molecule to do any volume of work is called energy. It is the strength held inside…

Q: 17. Please check to see if the following are balanced. If they are not, please balance them a. K +…

Q: 15) What 1H NMR spectral data is expected for the compound shown? Explain the reason for your…

A: 7

Q: Write a mass balance for a solution of Fe2(SO4)3 if the species are Fe3+, Fe(OH)2+, Fe(OH)2+,…

A: Mass balance states that the amount of species covey to a solution is equal to the addition of…

Q: The rate constant k for a certain reaction is measured at two different temperatures: temperature k…

Q: How many milliliters of a 12% (v/v) propyl alcohol solution would you need to obtain 4.5 mL of…

Q: Label the resonance structures in each pair as major, minor, or equal contributors to the hybrid.…

A: Steps to decide the more stable resonating structures: 1. Structure in which the octet of every…

Q: Will the following reaction occur? O NH O Yes O No EtOH cat. H₂SO4 H₂N O OEt

A: We have been given an organic reaction and we have been asked whether the given organic reaction…

Q: What is the smallest whole-number coefficient for H₂S when the equation H₂S + MnO₄⁻ → Mn²⁺ + SO₄²⁻…

A: Recall the given reaction, H2S + MnO4- → Mn2+ + SO42- We have…

Q: Give the hybridization for the Br in BrF4*. O sp O sp² O sp³d² O sp3 O sp³d

A: BrF4+ is a penta-atomic interhalogen. In BrF4+, Br is the central atom. In BrF4+, Br is in +1 state.

Q: Draw arrow-pushing mechanisms for the following reactions. Include all lone pairs and all formal…

A: Two questions based on reaction mechanisms. First question is about elimination reaction and the…

Q: Element "X" has 7 valence electrons. Element "R" has 5 valence electrons. Which of these is the…

A: Lewis Structure is a very simplified representation of the valence shell electrons in a molecule. It…

Q: Discuss the mechanisms and environmental implications of the photochemical formation of secondary…

A: Introduction:The photochemical formation of secondary pollutants in the atmosphere involves complex…

Q: Show the Claison product and then the reaction mechanism when (CH3)3CCO2CH3 reacts with CH₂CH₂CO₂CH3…

A: As per our guidelines We are supposed to answer only the first question, hence kindly repost the…

Q: Using the thermodynamic information in the ALEKS Data tab, calculate the boiling point of methanol…

Q: so its ok that the suzuki product doesnt have rings? I've only seen ring products so I thought it…

A: Suzuki reaction requires boronic acid and alkyl halide or aryl halide as reactant. In Suzuki…

Q: Enter your answer in the provided box. How many grams of sucrose (C12H₂2O11) must be added to 465 g…

Q: At room temperature, which of the following substances would compress most easily (its particles…

A: In the given question, we have to find out the substance which would compress easily when pressure…

Q: The equation defining density is written as follows: Density d= g = g ог mL cm 3 mass volume = g…

A: Density = Mass/Volume

Q: Match the image of the particles to the state of matter. :: Solid :: Liquid :: Gas

A: Molecules in solid state are very tightly packed , hence the space between the particles in solid…

Q: takes 0.571 L of 0.2 M NaOH to neutralize 9.6 L of an HCl solution, what is the concentration of…

A: Molarity= moles of Solute/Volume of solution

Q: = For a certain chemical reaction, the equilibrium constant k °c. Calculate the standard Gibbs free…

Q: Using the Nernst equation, calculate the total potential for the following cells: Cu²+ + (aq) (0.100…

Q: 1. a) Consider the following equilibrium: 2NO (B) + Cl2(g) 2NOCI (g) How will the amount of Cl₂ be…

A: According to Le Chatelier principle if a system is in equilibrium is subjected to change of…

Q: Select the correct Lewis Diagram for XeOF™ (be careful making your asnwer choices - the letters…

A: C

Q: Compare BF3 and NF3 • Bond Angle: [Select] • Hybridization: [Select] Polarity: [Select] [Select]…

A: Detail

Q: Why NaI is considered spectaor

A: Spectator ions are ions that do not take part in a chemical reaction and are found in solution both…

Q: 2. Calculate the AH for the reaction HCI(g) + NaNO₂(s)→ HNO₂(1) + NaCl(s) from the following data:…

Q: 6.6 An adiabatic vessel contains 1000 g of liquid aluminum at 700°C. Calculate the mass of Cr₂O3 at…

Q: What is the substance that is reduced in a redox reaction called? A B C D a reducing agent an…

A: Oxidation reduction reaction (Redox reaction) It can be defined as the chemical reaction in which…

Q: 2 NH3 (8) 37. N2(g) + 3H₂(g) For this reaction, if increase the pressure, which direction will the…

A: According to Le chateliers principle, when we disturb the equilibrium of reaction by known manner,…

Q: 2) A buffer solution contains 0.339 M ammonia. If 0.0248 moles of hydrochloric acid are added to…

Q: d) 8 11. What is the difference between Atomic Mass and Atomic Number? a) Atomic Mass is the number…

A: Atoms are composed of subatomic particles including protons, neutrons, and electrons. Protons are…

Q: Consider the following data for iron: atomic mass 55.845 electronegativity electron affinity…

A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…

Q: Match each of the following labeled molecules with the corresponding IR spectrum (Multiple answers…

A: An IR spectra is given and a set of compounds are given. We need to find this IR spectra refers to…

Q: What is the molar mass of butane, C4H10? Express your answer to four significant figures and include…

A: Molar mass of a compound is equal to the sum of the mass of each element present in the chemical…

Q: Draw six isomeric cyclopentanes of molecular formula C7H14. These will include four constitutional…

A: Constitutional isomers: They have same molecular formula but different connectivity of atoms or…

Question

100%

2. Explain why the following Williamson ether synthesis will not work.
1) NaH
2) Br-
OH
X
Propose an alternative synthesis for the desired target molecule by filling in the starting
material and the reagent or molecule needed for step 2 in the reaction conditions in the boxes
below.
1) NaH
2)

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Williamson ether synthesis

VIEW

Step 2: Use of different alkyl halide

VIEW

Solution

VIEW

Step by step

Solved in 3 steps with 3 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Protection of Groups in Organic Synthesis

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Draw the major organic product of the Bronsted acid-base reaction. Include all lone pairs and charges as appropriate. Ignore any counterions. ] NaH OH
In each reaction box, place the best reagent and conditions from the list below. Ph 1) 2) 3)
4. Provide a synthetic route to the following molecule using benzene and cyclohexane. Reagents cannot contain more than one carbon. Provide a mechanism for the last step of your synthetic route.
Complete the following reaction O NH₂ CH3 NH₂ CH3 Br CH3 NH₂ CH3 NH 2 CH₂ Br 1) HNO/H₂SO4 2) HBr/CuBr NO₂ Br NO₂
The compound below can be prepared with an alkyl iodide and a suitable nucleophile. Identify the alkyl iodide and the nucleophile that you would use. For an anionic nucleophile, you do not need to draw the counterion. Alkyl iodide: OH Draw Your Solution Nucleophile: Draw Your Solution SUPPORT
Construct a three-step synthesis of 1-bromopropane from propane by dragging the appropriate formulas into the bins. Note that each bin willl hold only one item, and not all of the given reagents or structures will be used. Reactant Reagent 1 Step 1 Product Reagent 2 Step 2 Product Reagent 3 Final Product (1-bromopropane) (propane) Br2 Br2 (CH)3CO K HBr ROOR HBr NBS ROOR HaC Нас Нас, Нас Нас НаС. hv CH2 CH2 CH Нс CH-Br CH-Br CH Нас Нас, нC Нас НаС Br Br Br
Which set of reagents are required to complete the following reaction? The reaction may take multiple steps. H3C CH3 1) LiAlH4 2) H₂O 1)Pyridine/heat 2) CH3CH3 1) LDA/THF 2) CH3CH₂I 1) NaCN 2) CH3I H3C H₂ H₂ CH3
Draw the major product of this reaction. Ignore inorganic byproducts. 1. Hg(OAc)2, H₂O 2. NaBH4, NaOH Drawing at
6. Multi Step Synthesis. Propose a synthetic route from the reactant to the product using any reagents you need. Nalt LINH4
rank these from least to most reactive in nucleophilic acyl substitution with a nucleophile I)CH3COOC2H5 II) CH3COO-Na+ III)CH3COCl IV) CH3CONH2
4) Design a complete synthesis for each of the following transformations. More than one step is required. SO3H = Br. 0=d H₂N CI NH₂ = 0= O₂N 0= OH NO₂ NO₂ سلم 'Br OH for
The following two step synthesis reduces the amount of waste generated by incorporating most of the atoms in the reagents into the products. Predict the products of each step.