. BMI (Body mass index) is the ratio mass in kilograms to the square of height in kilograms Between 18 and 25 is normal. Below 18 is low and above 25 is high. You are looking for SNPS that correlate with low BMI. You look at a number of individuals and look at their BMIS And look at several SNPS. Which SNP best correlates with low BMI? BMI 25 16 31 15 26 SNP1 A A A A T SNP2 G G G C C SNP3 T T T C C SNP4 A cl A C A What is exome sequencing? Give an application.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter4: Pedigree Analysis In Human Genetics
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Problem 4QP: Pedigree Analysis Is a Basic Method in Human Genetic: What does OMIM stand for? What kinds of...
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. BMI (Body mass index) is the ratio mass in kilograms to the square of height in
kilograms Between 18 and 25 is normal. Below 18 is low and above 25 is high.
You are looking for SNPS that correlate with low BMI. You look at a number of
individuals and look at their BMIS And look at several SNPS. Which SNP best
correlates with low BMI?
1-1
1-2
2-1
2-2
BMI
25
16
31
2-3
2-4
2-5
3-5
3-6
15
26
SNP1
A
A
A
A
T
3,7
4,5
3
2,3
7
4,9
4
4,7
SNP2
B
3
G
2,6
2,6
3,6
2,3
3,6
3,4
4,6
3
G
G
C
C
What is exome sequencing? Give an application.
OOOO D
5 The above pedigree is an autosomal dominant trait. You are trying to identify the gene
responsible, so you start by looking at some variable markers to determine which ones might
map near the disease gene. You look at 6 markers (A-F). The numbers refer to sizes in 1000 o
bases. Individuals in bold have the trait Which marker (A-F) is most likely to be associated w
the trait
Individual A
2
SNP3
T
T
T
C
C
C
1,5
2,4
3,7
1,4
2,5
1,2
4,6
2,6
1,4
SNP4
D
1,6
4,5
8,9
5,6
4,6
1,4
A
3,8
1,8
4,8
cl
A
C
A
E
3,7
4,8
2,6
3,4
3,4
4,7
5,8
5,7
4,7
F
2,9
4,7
1,3
2,4
7,9
2,4
2,9
2,9
4,9
Transcribed Image Text:. BMI (Body mass index) is the ratio mass in kilograms to the square of height in kilograms Between 18 and 25 is normal. Below 18 is low and above 25 is high. You are looking for SNPS that correlate with low BMI. You look at a number of individuals and look at their BMIS And look at several SNPS. Which SNP best correlates with low BMI? 1-1 1-2 2-1 2-2 BMI 25 16 31 2-3 2-4 2-5 3-5 3-6 15 26 SNP1 A A A A T 3,7 4,5 3 2,3 7 4,9 4 4,7 SNP2 B 3 G 2,6 2,6 3,6 2,3 3,6 3,4 4,6 3 G G C C What is exome sequencing? Give an application. OOOO D 5 The above pedigree is an autosomal dominant trait. You are trying to identify the gene responsible, so you start by looking at some variable markers to determine which ones might map near the disease gene. You look at 6 markers (A-F). The numbers refer to sizes in 1000 o bases. Individuals in bold have the trait Which marker (A-F) is most likely to be associated w the trait Individual A 2 SNP3 T T T C C C 1,5 2,4 3,7 1,4 2,5 1,2 4,6 2,6 1,4 SNP4 D 1,6 4,5 8,9 5,6 4,6 1,4 A 3,8 1,8 4,8 cl A C A E 3,7 4,8 2,6 3,4 3,4 4,7 5,8 5,7 4,7 F 2,9 4,7 1,3 2,4 7,9 2,4 2,9 2,9 4,9
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